Cilomilast

Cilomilast Structure
Cilomilast structure
Common Name Cilomilast
CAS Number 153259-65-5 Molecular Weight 343.417
Density 1.2±0.1 g/cm3 Boiling Point 549.1±50.0 °C at 760 mmHg
Molecular Formula C20H25NO4 Melting Point 157ºC
MSDS Chinese USA Flash Point 285.9±30.1 °C

Blockade of PDE4B limits lung vascular permeability and lung inflammation in LPS-induced acute lung injury.

Biochem. Biophys. Res. Commun. 450(4) , 1560-7, (2014)

Acute lung injury (ALI), acute respiratory distress syndrome (ARDS), is actually involved in an ongoing and uncontrolled inflammatory response in lung tissues. Although extensive studies suggested that phospodiesterase type 4B (PDE4B) may be related to inflam...