(-)-n-methylphysostigmine

(-)-n-methylphysostigmine Structure
(-)-n-methylphysostigmine structure
Common Name (-)-n-methylphysostigmine
CAS Number 103877-07-2 Molecular Weight 289.37300
Density 1.152g/cm3 Boiling Point 406.7ºC at 760 mmHg
Molecular Formula C16H23N3O2 Melting Point N/A
MSDS USA Flash Point 199.8ºC

Anti-proliferative effect and induction of apoptosis in androgen-independent human prostate cancer cells by 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one.

Molecules 20(2) , 3406-30, (2015)

Curcumin has poor in vivo absorption and bioavailability, highlighting a need for new curcumin analogues with better characteristics in these aspects. The aim of this study is to determine the anti-cancer properties of four selected curcumin analogues, on the...

Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay.

PLoS ONE 10(4) , e0124742, (2015)

Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether levosimendan could modulate the cross-talk between apoptos...

Inhibition of acetylcholinesterase from electric eel by (-)-and (+)-physostigmine and related compounds.

FEBS Lett. 201 , 190-192, (1986)

Unnatural (+)-physostigmine (2) inhibited acetylcholinesterase (AChE) from electric eel considerably less than natural (-)-physostigmine (1), but 2 may because of its possible lower toxicity still be an interesting anticholinesterase agent. (-)-Eseroline (3),...

Inhibition of acetylcholinesterase by new physostigmine derivatives.

Biomed. Biochim. Acta 47 , 285-288, (1988)

The kinetics of inhibition of acetylcholinesterase (AChE, EC 3.1.1.7) from electric eel by new physostigmine derivatives in which the methylcarbamic group has been substituted with monoalkylcarbamic, dialkylcarbamic and phenylcarbamic groups was studied. The ...