kb-NB142-70
kb-NB142-70 structure
|
Common Name | kb-NB142-70 | ||
|---|---|---|---|---|
| CAS Number | 1233533-04-4 | Molecular Weight | 251.325 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 601.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C11H9NO2S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 317.8±31.5 °C | |
|
Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro.
PLoS ONE 10(4) , e0124234, (2015) Emerging evidence suggests that the vascular endothelial growth factor receptor 2 (VEGFR2) and protein kinase D1 (PKD1) signaling axis plays a critical role in normal and pathological angiogenesis and inflammation related processes. Despite all efforts, the c... |
|
|
PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester.
Int. J. Biochem. Cell Biol. 60 , 34-42, (2015) Protein kinase D1 (PKD1) is increasingly implicated in multiple biological and molecular events that regulate the proliferation or invasiveness in several cancers. However, little is known about the expression and functions of PKD1 in non-small cell lung canc... |
|
|
Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552.
Am. J. Physiol. Cell Physiol. 310 , C542-57, (2016) Given the fundamental role of β-catenin signaling in intestinal epithelial cell proliferation and the growth-promoting function of protein kinase D1 (PKD1) in these cells, we hypothesized that PKDs mediate cross talk with β-catenin signaling. The results pres... |