Tocopheryl acetate
Tocopheryl acetate structure
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Common Name | Tocopheryl acetate | ||
|---|---|---|---|---|
| CAS Number | 7695-91-2 | Molecular Weight | 472.743 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 485.3±0.0 °C at 760 mmHg | |
| Molecular Formula | C31H52O3 | Melting Point | -28ºC | |
| MSDS | Chinese USA | Flash Point | 235.6±24.7 °C | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Multi-centre observational study of transplacental transmission of influenza antibodies following vaccination with AS03(A)-adjuvanted H1N1 2009 vaccine.
PLoS ONE 8(1) , e47448, (2013) Illness and death from influenza increase during pregnancy. In the United Kingdom pregnant women were targeted in a national programme for vaccination during the H1N1 2009-10 pandemic.In this study, pregnant women were recruited in labour from November 9, 200... |
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Preparation of alginate beads containing a prodrug of diethylenetriaminepentaacetic acid.
Carbohydr. Polym. 92(2) , 1915-20, (2013) A penta-ethyl ester prodrug of the radionuclide decorporation agent diethylenetriaminepentaacetic acid (DTPA), which exists as an oily liquid, was encapsulated in alginate beads by the ionotropic gelation method. An optimal formulation was found by varying in... |
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Phytantriol-based in situ liquid crystals with long-term release for intra-articular administration.
AAPS PharmSciTech 16 , 846-54, (2015) The purpose of this study was to develop an injectable in situ liquid crystal formulation for intra-articular (IA) administration, and in situ forming a viscous liquid crystalline gel with long-term release of sinomenine hydrochloride (SMH) upon water absorpt... |
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Microbeads: a novel multiparticulate drug delivery technology for increasing the solubility and dissolution of celecoxib.
Pharm. Dev. Technol. 20(2) , 211-8, (2015) The purpose of this study was to develop a novel multipaticulate drug delivery technology suitable for the delivery of pre-solubilized celecoxib to the gastrointestinal tract and more specifically to the colon. The solubility of celecoxib in a range of oils, ... |
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Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes.
Biochem. Pharmacol. 86(1) , 67-79, (2013) There is some evidence that oxidized derivatives of cholesterol, 7-ketocholesterol (7KC) and 7β-hydroxycholesterol (7βOHC), are increased in the plasma of patients with neurodegenerative diseases associated with demyelinization of the central nervous system (... |
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New strategy of α- and γ-tocopherol to prevent contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures.
Nephrol. Dial. Transplant. 28(2) , 337-44, (2013) Contrast-induced acute kidney injury (CI- AKI) increases the likelihood of patient morbidity and mortality following coronary procedures. Volume supplement with saline is the standard treatment to prevent CI-AKI. Additional antioxidant prophylaxis has often y... |
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Exposure to 1800 MHz radiofrequency electromagnetic radiation induces oxidative DNA base damage in a mouse spermatocyte-derived cell line.
Toxicol. Lett. 218(1) , 2-9, (2013) Whether exposure to radiofrequency electromagnetic radiation (RF-EMR) emitted from mobile phones can induce DNA damage in male germ cells remains unclear. In this study, we conducted a 24h intermittent exposure (5 min on and 10 min off) of a mouse spermatocyt... |
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Inhibitory effects of in vivo oxidized high-density lipoproteins on platelet aggregation: evidence from patients with abetalipoproteinemia.
FASEB J. 27(7) , 2855-61, (2013) There is evidence that high-density lipoproteins (HDLs) may regulate platelet function, but disparate results exist regarding the effects of oxidized HDLs on platelets. The objective of our study was to determine the role of in vivo oxidized HDLs on platelet ... |
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Alteration of α-tocopherol-associated protein (TAP) expression in human breast epithelial cells during breast cancer development.
Food Chem. 138(2-3) , 1015-21, (2013) Breast cancer is the most common malignancy among women and has an age-specific incidence profile. Over the last decade, many studies have demonstrated the anticancer activity of α-tocopherol, the main and most active form of natural vitamin E. α-Tocopherol-a... |