![]() Fmoc-Pro-OH structure
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Common Name | Fmoc-Pro-OH | ||
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CAS Number | 71989-31-6 | Molecular Weight | 337.369 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 548.6±43.0 °C at 760 mmHg | |
Molecular Formula | C20H19NO4 | Melting Point | 112-115ºC | |
MSDS | Chinese USA | Flash Point | 285.6±28.2 °C |
Metabolomic serum profiling detects early-stage high-grade serous ovarian cancer in a mouse model.
J. Proteome Res. 14(2) , 917-27, (2015) Ovarian cancer is a deadly disease killing more than any other gynecologic cancer. Nonspecific symptoms, combined with a lack of early detection methods, contribute to late diagnosis and low five-year survival rates. High-grade serous carcinoma (HGSC) is the ... |
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Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.
Macromol. Biosci. 15(1) , 52-62, (2015) To address the downside of conventional photo-patterning which can alter the chemical composition of protein scaffolds, we developed a non-covalent photo-patterning strategy for gelatin (denatured collagen) hydrogels that utilizes UV activated triple helical ... |
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Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.
J. Med. Chem. 53 , 2215-26, (2010) We report the molecular design and synthesis of EG00229, 2, the first small molecule ligand for the VEGF-A receptor neuropilin 1 (NRP1) and the structural characterization of NRP1-ligand complexes by NMR spectroscopy and X-ray crystallography. Mutagenesis stu... |
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Cell-penetrating apoptotic peptide/p53 DNA nanocomplex as adjuvant therapy for drug-resistant breast cancer.
Mol. Pharm. 11(10) , 3352-60, (2014) Drug resistance becomes a formidable challenge against effective cancer therapy. Defective apoptosis in cancer cells is a key factor responsible for chemoresistance or radioresistance. Promoting apoptosis is an important method to sensitize the resistant cell... |
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Complete ON/OFF photoswitching of the motility of a nanobiomolecular machine.
ACS Nano 8(5) , 4157-65, (2014) To apply motor proteins as natural nanomolecular machines to transporting systems in nanotechnology, complete temporal control over ON/OFF switching of the motility is necessary. We have studied the photoresponsive inhibition properties of azobenzene-tethered... |
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Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo.
PLoS ONE 4 , e7191, (2009) Temporins are antimicrobial peptides secreted by the granular glands of the European red frog (Rana temporaria). They are 10-14 amino acid long polypeptides active prevalently against gram positive bacteria. This study shows that a synthetic temporin B analog... |
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Gas-phase fragmentation of oligoproline peptide ions lacking easily mobilizable protons.
J. Am. Soc. Mass Spectrom. 24 , 846-56, (2013) The fragmentation of peptides containing quaternary ammonium group, but lacking easily mobilizable protons, was examined with the aid of deuterium-labeled analogs and quantum-chemical modeling. The fragmentation of oligoproline containing quaternary ammonium ... |