1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC structure
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Common Name | 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC | ||
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| CAS Number | 26853-31-6 | Molecular Weight | 760.076 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H82NO8P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.
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Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.
Pharm. Res. 32(5) , 1546-56, (2015) To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide (penetratin), all 5(6)-carboxytetramethylrhodamine-labeled,... |
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The cytolytic activity of vaginolysin strictly depends on cholesterol and is potentiated by human CD59.
Toxins (Basel.) 7(1) , 110-28, (2015) Gardnerella vaginalis produces cytolysin vaginolysin (VLY), which has been suggested to be a contributor to bacterial vaginosis pathogenesis. VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of cholesterol-dep... |
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Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.
Nature Chemistry 6(10) , 885-92, (2014) Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity ... |
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Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane.
Bioorg. Med. Chem. 23 , 5782-8, (2015) Amphotericin B (AmB) is a polyene macrolide antibiotic widely used to treat mycotic infections. In this paper, we focus on the role of the polyol moiety of AmB in sterol selectivity using 7-oxo-AmB, 7α-OH-AmB, and 7β-OH-AmB. The 7-OH analogs were prepared fro... |
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Defective functionality of HDL particles in familial apoA-I deficiency: relevance of alterations in HDL lipidome and proteome.
J. Lipid Res. 55(12) , 2509-20, (2014) To evaluate functional and compositional properties of HDL in subjects from a kindred of genetic apoA-I deficiency, two homozygotes and six heterozygotes, with a nonsense mutation at APOA1 codon -2, Q[-2]X, were recruited together with age- and sex-matched he... |
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Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
Biochim. Biophys. Acta 1828(9) , 2152-63, (2013) Submillimolar concentrations of cytotoxic bile acids (BAs) induce cell death via apoptosis. On the other hand, several cytoprotective BAs were shown to prevent apoptosis in the same concentration range. Still, the mechanisms by which BAs trigger these opposit... |
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Phospholipid lateral diffusion in phosphatidylcholine-sphingomyelin-cholesterol monolayers; effects of oxidatively truncated phosphatidylcholines.
Biochim. Biophys. Acta 1848(1 Pt A) , 167-73, (2015) Oxidative stress is involved in a number of pathological conditions and the generated oxidatively modified lipids influence membrane properties and functions, including lipid-protein interactions and cellular signaling. Brewster angle microscopy demonstrated ... |
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Curvature sensing MARCKS-ED peptides bind to membranes in a stereo-independent manner.
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Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.
Sci. Rep. 5 , 16432, (2015) A central tenet of signal transduction in eukaryotic cells is that extra-cellular ligands activate specific cell surface receptors, which orchestrate downstream responses. This ''protein-centric" view is increasingly challenged by evidence for the involvement... |