APM

APM Structure
APM structure
Common Name APM
CAS Number 627-76-9 Molecular Weight 175.182
Density 1.3±0.1 g/cm3 Boiling Point 378.5±37.0 °C at 760 mmHg
Molecular Formula C7H13NO4 Melting Point 223 °C (dec.)(lit.)
MSDS USA Flash Point 182.7±26.5 °C

Peptides containing 2-aminopimelic acid. Synthesis and study of in vitro effects on bacterial cells.

Int. J. Pept. Protein Res. 37 , 103-111, (1991)

Taking advantage of the peptide transport strategy, we have designed and synthesized several new peptides containing 2-aminopimelic acid (Apm), an inhibitor of the diaminopimelate pathway in bacteria: L-Lys-ambo-Apm, ambo-Apm-L-Lys, L-Lys-L-Ala-ambo-Apm, ambo...

Peptides of 2-aminopimelic acid: antibacterial agents that inhibit diaminopimelic acid biosynthesis.

J. Med. Chem. 29 , 89-95, (1986)

Succinyl-CoA:tetrahydrodipicolinate-N-succinyltransferase is a key enzyme in the biosynthesis of diaminopimelic acid (DAP), a component of the cell wall peptidoglycan of nearly all bacteria. This enzyme converts the cyclic precursor tetrahydrodipicolinic acid...

N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis.

Carcinogenesis 35(10) , 2264-72, (2014)

Platinum resistance is the most crucial problem for treatment of ovarian cancer. There is a clinical need for new treatment strategies which overcome platinum resistance. Recently high level of AKT was shown to be involved in platinum resistance and furthermo...