Zinpyr-1
Zinpyr-1 structure
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Common Name | Zinpyr-1 | ||
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| CAS Number | 288574-78-7 | Molecular Weight | 823.721 | |
| Density | 1.49g/cm3 | Boiling Point | 931.2±65.0 °C at 760 mmHg | |
| Molecular Formula | C46H36Cl2N6O5 | Melting Point | 185-187ºC | |
| MSDS | Chinese USA | Flash Point | 517.0±34.3 °C | |
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Chronic alcohol administration causes expression of calprotectin and RAGE altering the distribution of zinc ions in mouse testis.
Syst. Biol. Reprod. Med. 61(1) , 18-25, (2014) Several studies reported that chronic alcohol consumption alters the intestinal mucosa barrier, and subsequent entrance of endotoxins into the bloodstream. In many tissues endotoxin exposure causes the expression of calprotectin (CP) and the receptor for adva... |
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tert-Butylhydroquinone mobilizes intracellular-bound zinc to stabilize Nrf2 through inhibiting phosphatase activity.
Am. J. Physiol. Cell Physiol. 309 , C148-58, (2015) The nuclear factor erythroid 2-related factor 2 (Nrf2) is required to combat increases in oxidative stress. The chemical compound tert-butylhydroquinone (tBHQ) can downregulate Kelch-like ECH-associated protein 1 (Keap1), a repressor of Nrf2, thus maintaining... |
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Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.
Neurobiol. Dis. 81 , 4-13, (2015) The aim of this study was to investigate the role of the synaptic metabotropic zinc receptor mZnR/GPR39 in physiological adaptation to epileptic seizures. We previously demonstrated that synaptic activation of mZnR/GPR39 enhances inhibitory drive in the hippo... |
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Molecular Basis of Transient Neonatal Zinc Deficiency: NOVEL ZnT2 MUTATIONS DISRUPTING ZINC BINDING AND PERMEATION.
J. Biol. Chem. 291 , 13546-59, (2016) A gradually increasing number of transient neonatal zinc deficiency (TNZD) cases was recently reported, all of which were associated with inactivating ZnT2 mutations. Here we characterized the impact of three novel heterozygous ZnT2 mutations G280R, T312M, an... |