emedastine fumarate
emedastine fumarate structure
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Common Name | emedastine fumarate | ||
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| CAS Number | 87233-62-3 | Molecular Weight | 534.55900 | |
| Density | N/A | Boiling Point | 446.6ºC at 760 mmHg | |
| Molecular Formula | C25H34N4O9 | Melting Point | 148-151° | |
| MSDS | N/A | Flash Point | N/A | |
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Efficacy of olopatadine HCI 0.1%, ketotifen fumarate 0.025%, epinastine HCI 0.05%, emedastine 0.05% and fluorometholone acetate 0.1% ophthalmic solutions for seasonal allergic conjunctivitis: a placebo-controlled environmental trial.
Acta Ophthalmol. 87(5) , 549-54, (2009) We aimed to compare the clinical efficacy and ocular surface variables of olopatadine, ketotifen fumarate, epinastine, emedastine and fluorometholone acetate ophthalmic solutions in preventing the signs and symptoms of seasonal allergic conjunctivitis (SAC).T... |
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Emedastine difumarate versus loratadine in chronic idiopathic urticaria: a randomized, double-blind, controlled European multicentre clinical trial.
Eur. J. Dermatol. 16(6) , 649-54, (2006) Emedastine difumarate (2 mg b.i.d.) was compared to loratadine (10 mg o.d.) in a randomized, double-blind, multicentre trial for 4 weeks in 192 patients with idiopathic chronic urticaria. After one week of treatment significant differences were recorded: body... |
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Suplatast tosilate inhibits eosinophil production and recruitment into the skin in murine contact sensitivity.
Clin. Immunol. 108(3) , 257-62, (2003) Antiallergic drugs and antihistamines have been widely used for controlling mucosal allergic diseases in which eosinophilia is prominent. Although H1-receptor antagonists are effective for treating histamine-induced wheal and itch in urticaria, the effects of... |
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[In vitro effects of antiallergic eyedrops on complement activation induced by particulate matter].
J. Fr. Ophtalmol. 26(4) , 328-36, (2003) Recent decades have been marked by an increasing number of patients suffering from ocular allergic-like symptoms without being associated with an increase in IgE levels. These symptoms include heaviness of the lid, foreign body sensation, burning, stinging an... |
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A randomized, double-blind, placebo-controlled comparison of emedastine 0.05% ophthalmic solution with loratadine 10 mg and their combination in the human conjunctival allergen challenge model.
Clin. Ther. 24(3) , 445-56, (2002) When selecting treatment for allergic conjunctivitis, a primary concern is whether to choose local or systemic therapy.This study compared the efficacy of topical emedastine 0.05% ophthalmic solution with that of oral loratadine 10 mg and their combination in... |
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Comparison of emedastine 0.05% or nedocromil sodium 2% eye drops and placebo in controlling local reactions in subjects with allergic conjunctivitis.
Eur. J. Ophthalmol. 12(4) , 262-6, (2002) To assess the efficacy of nedocromil sodium 2% eye drops and emedastine difumarate 0.05% eye drops in controlling the ocular allergic reaction induced by conjunctival allergen challenge (CAC).Thirty subjects with a personal history of allergic conjunctivitis ... |
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The oral iron chelator deferasirox induces apoptosis in myeloid leukemia cells by targeting caspase.
Acta Haematol. 126(4) , 241-5, (2011)
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Clinical study of the therapeutic efficacy and safety of emedastine difumarate versus cetirizine in the treatment of seasonal allergic rhinitis.
Arzneimittelforschung 54(10) , 666-72, (2004) The therapeutic efficacy and tolerability of emedastine difumarate (CAS 87233-62-3) in male and female Caucasian patients with seasonal allergic rhinitis as compared to cetirizine (CAS 83881-51-0) was evaluated.The study was designed as a double-blind, random... |
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High-performance liquid chromatography-electrospray ionization-mass spectrometric determination of emedastine difumarate in human plasma and its pharmacokinetics.
J. Chromatogr. Sci. 45(3) , 158-64, (2007) A selective and sensitive method employing high-performance liquid chromatography (HPLC)-electrospray ionization (ESI)-mass spectrometry is developed and validated for the determination of emedastine difumarate in human plasma. With naphazoline hydrochloride ... |
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Clinical study of the therapeutic efficacy and safety of emedastine difumarate versus terfenadine in the treatment of seasonal allergic rhinitis.
Arzneimittelforschung 54(10) , 660-5, (2004) Emedastine is a new H1-receptor antagonist endowed with potent and selective antihistamine activity. The aim of this study was to evaluate the therapeutic efficacy and tolerability of emedastine difumarate (CAS 87233-62-3) in Caucasian patients in the treatme... |