Cyclazosin hydrochloride
Cyclazosin hydrochloride structure
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Common Name | Cyclazosin hydrochloride | ||
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| CAS Number | 146929-33-1 | Molecular Weight | 473.953 | |
| Density | N/A | Boiling Point | 691.1ºC at 760 mmHg | |
| Molecular Formula | C23H28ClN5O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 371.7ºC | |
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Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist.
J. Med. Chem. 39 , 4602, (1996) The enantiomers of [4-(4-amino-6, 7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin-1-yl]-fu ran- 2-ylmethanone (cyclazosin, 1) were synthesized from the chiral furan-2-yl(cis-octahydroquinoxalin-1-yl)methanone [(+)-2 and (-)-2], which were obtained by reso... |
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Receptor binding profile of cyclazosin, a new alpha 1B-adrenoceptor antagonist.
Eur. J. Pharmacol. 287 , 13-16, (1995) The binding profile of cyclazosin, a new prazosin-related alpha 1-adrenoceptor antagonist, at alpha 1-, alpha 2-adrenoceptors, dopamine D2 and 5-HT1A receptors was compared to that of 5-methylurapidil, spiperone, risperidone and other prazosin-related ligands... |
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