Boc-D-FMK

Boc-D-FMK Structure
Boc-D-FMK structure
Common Name Boc-D-FMK
CAS Number 187389-53-3 Molecular Weight 263.263
Density 1.1±0.1 g/cm3 Boiling Point 383.5±37.0 °C at 760 mmHg
Molecular Formula C11H18FNO5 Melting Point N/A
MSDS Chinese USA Flash Point 185.7±26.5 °C

C1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells.

PLoS ONE 6 , e20053, (2011)

Diacylglycerol (DAG)-mediated signaling pathways, such as those mediated by protein kinase C (PKC), are central in regulating cell proliferation and apoptosis. DAG-responsive C1 domains are therefore considered attractive drug targets. Our group has designed ...

Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats.

Neuroreport 12 , 541, (2001)

Following ventral root avulsion in neonatal animals, the degeneration of spinal motoneurons occurs by an apoptotic-like morphological pathway. In adult animals, however, the mechanism of degeneration of injured motoneurons is still controversial. Because casp...

The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo.

PLoS Genet. 5 , e1000518, (2009)

Females homozygous for a mutation in cellular island (cei) produce embryos with defects in cytokinesis during early development. Analysis of the cytoskeletal events associated with furrow formation reveal that these defects include a general delay in furrow i...

Adiponectin-induced antitumor activity on prostatic cancers through inhibiting proliferation.

Cell Biochem. Biophys. 70(1) , 461-5, (2014)

Adiponectin, an adipose tissue-derived hormone, has been studied intensively for the past decade because of its anti-inflammatory, anti-atherogenic, and anti-diabetic properties. Recent advances suggest that adiponectin also plays an important role in the dev...