青霉素酰胺酶 来源于大肠杆菌

更新时间:2024-01-02 10:39:30

青霉素酰胺酶 来源于大肠杆菌结构式
青霉素酰胺酶 来源于大肠杆菌结构式
品牌特惠专场
常用名 青霉素酰胺酶 来源于大肠杆菌 英文名 Penicillin amidase
CAS号 9014-06-6 分子量 N/A
密度 N/A 沸点 N/A
分子式 N/A 熔点 N/A
MSDS 美版 闪点 N/A

 青霉素酰胺酶 来源于大肠杆菌用途


青霉素酰胺酶(青霉素酰化酶)是一种切割青霉素酰基侧链的酶。青霉素酰胺酶可用于生产6-氨基青霉烷酸。青霉素酰胺酶也可用于拆分外消旋混合物、肽合成和半合成β-内酰胺抗生素的合成[1][2][3]。

 青霉素酰胺酶 来源于大肠杆菌名称

中文名 青霉素(酰胺)酶
英文名 EC 3.5.1.11
英文别名 更多

 青霉素酰胺酶 来源于大肠杆菌生物活性

描述 青霉素酰胺酶(青霉素酰化酶)是一种切割青霉素酰基侧链的酶。青霉素酰胺酶可用于生产6-氨基青霉烷酸。青霉素酰胺酶也可用于拆分外消旋混合物、肽合成和半合成β-内酰胺抗生素的合成[1][2][3]。
相关类别
参考文献

[1]. Duggleby HJ, et al. Penicillin acylase has a single-amino-acid catalytic centre. Nature. 1995 Jan 19;373(6511):264-8.  

[2]. Avinash VS, et al. Penicillin acylases revisited: importance beyond their industrial utility. Crit Rev Biotechnol. 2016;36(2):303-16.  

[3]. Tishkov VI, et al. Protein engineering of penicillin acylase. Acta Naturae. 2010 Jul;2(3):47-61.  

 青霉素酰胺酶 来源于大肠杆菌物理化学性质

外观性状 lyophilized powder
储存条件 2-8°C

 青霉素酰胺酶 来源于大肠杆菌安全信息

危害码 (欧洲) Xn
风险声明 (欧洲) 42/43
安全声明 (欧洲) 22-36/37
危险品运输编码 NONH for all modes of transport
WGK德国 3

 青霉素酰胺酶 来源于大肠杆菌文献36

更多文献
Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity.

Biochem. J. 451(2) , 217-26, (2013)

The crystal structure of the wild-type form of glutaryl-7-ACA (7-aminocephalosporanic acid) acylase from Pseudomonas N176 and a double mutant of the protein (H57βS/H70βS) that displays enhanced cataly...

Enantioselective acylation of β-phenylalanine acid and its derivatives catalyzed by penicillin G acylase from Alcaligenes faecalis.

Prep Biochem Biotechnol. 43(2) , 207-16, (2013)

This study developed a simple, efficient method for producing racemic β-phenylalanine acid (BPA) and its derivatives via the enantioselective acylation catalyzed by the penicillin G acylase from Alcal...

Engineering the substrate specificity of a thermophilic penicillin acylase from thermus thermophilus.

Appl. Environ. Microbiol. 79(5) , 1555-62, (2013)

A homologue of the Escherichia coli penicillin acylase is encoded in the genomes of several thermophiles, including in different Thermus thermophilus strains. Although the natural substrate of this en...

 青霉素酰胺酶 来源于大肠杆菌英文别名

EINECS 232-753-8