METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-

更新时间：2024-01-08 16:30:59

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式	常用名	METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-	英文名	METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-
	CAS号	890028-66-7	分子量	377.43300
	密度	N/A	沸点	N/A
	分子式	C₁₈H₂₀FN₃O₃S	熔点	N/A
	MSDS	N/A	闪点	N/A

英文名	N-[4-(4-fluorophenyl)-5-[(E)-3-oxoprop-1-enyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
中文别名	瑞舒伐他汀钙中间体
英文别名	更多

分子式	C₁₈H₂₀FN₃O₃S
分子量	377.43300
精确质量	377.12100
PSA	88.61000
LogP	4.09480

N-[4-(4-fluorophenyl)-5-[(E)-3-hydroxyprop-1-enyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide结构式

N-[4-(4-fluorop...

910867-08-2

~96%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：Dandala, Ramesh; Mallela, Sambhu Prasad Sarma; Garimella, Narayan K.A.S.S.; Nandi, Sukumar; Buridipad, Sunil Kumar; Nangi, Gangadhar Bhima Shankar; Meenakshisunderam, Sivakumaran Patent: US2010/48899 A1, 2010 ; Location in patent: Page/Page column 11 ;

trans-N-(5-(2-cyanovinyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide结构式

trans-N-(5-(2-c...

901765-35-3

~76%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：ASTRAZENECA UK LIMITED Patent: WO2007/7119 A1, 2007 ; Location in patent: Page/Page column 6; 25-26 ; WO 2007/007119 A1

1-[4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methylsulfonyl)amino]-pyrimidin-5-yl]-ethene结构式

1-[4-(4-fluorop...

1220122-72-4

1-[4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-(methylsulfonyl)amino]-pyrimidin-5-yl]-1-hydroxyethane结构式

1-[4-(4-fluorop...

1220122-71-3

N,N-二甲基甲酰胺结构式

N,N-二甲基甲酰胺

68-12-2

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：AUROBINDO PHARMA LIMITED; MALLELA, Sambhu Prasad Sarma; NANDI, Sukumar; NANGI, Gangadhara Bhima Shankar; ANANTA, Rani; MEENAKSHISUNDERAM, Sivakumaran Patent: WO2010/38124 A1, 2010 ; Location in patent: Page/Page column 19-20 ;

1-(4-氟苯基)-4-甲基-1,3-戊二酮(洛伐他汀中间体)结构式

1-(4-氟苯基)-4-甲基-...

114433-94-2

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

2-allyl-1-(4-fluorophenyl)-4-methylpentane-1,3-dione结构式

2-allyl-1-(4-fl...

1356998-74-7

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

5-allyl-4-(4-fluorophenyl)-6-isopropyl-N-methylpyrimidin-2-amine结构式

5-allyl-4-(4-fl...

1356998-75-8

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

N-(5-allyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide结构式

N-(5-allyl-4-(4...

1356998-76-9

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

(E)-N-(4-(4-fluorophenyl)-5-(3-bromoprop-1-enyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide结构式

(E)-N-(4-(4-flu...

1356998-82-7

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

N-(4-(4-fluorophenyl)-6-isopropyl-5-(oxiran-2-ylmethyl)pyrimidin-2-yl)-N-methylmethanesulfonamide结构式

N-(4-(4-fluorop...

1356998-78-1

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-结构式

METHANESULFONAM...

890028-66-7

文献：LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

上游产品 8
CAS号910867-08-2 N-[4-(4-fluorop... CAS号1220122-72-4 1-[4-(4-fluorop... CAS号1220122-71-3 1-[4-(4-fluorop... CAS号68-12-2 N,N-二甲基甲酰胺
CAS号114433-94-2 1-(4-氟苯基)-4-甲基-... CAS号1356998-74-7 2-allyl-1-(4-fl... CAS号1356998-75-8 5-allyl-4-(4-fl... CAS号1356998-76-9 N-(5-allyl-4-(4...
下游产品 1
CAS号901765-36-4 (5S)-7-[4-(4-氟苯...

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-3-oxo-1-propenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide

N-[4-(4-Fluorophenyl)-6-isopropyl-5-[(1E)-3-oxo-1-propenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide

(2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal

(2E)-3-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}propenal

3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(2E)-propenal

4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-mesylamino)pyrimidin-5-propenal

(E)-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide

trans-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide