METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-

Modify Date: 2024-01-08 16:30:59

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure
METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- structure
Common Name METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-
CAS Number 890028-66-7 Molecular Weight 377.43300
Density N/A Boiling Point N/A
Molecular Formula C18H20FN3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name N-[4-(4-fluorophenyl)-5-[(E)-3-oxoprop-1-enyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C18H20FN3O3S
Molecular Weight 377.43300
Exact Mass 377.12100
PSA 88.61000
LogP 4.09480

 Synthetic Route

~96%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: Dandala, Ramesh; Mallela, Sambhu Prasad Sarma; Garimella, Narayan K.A.S.S.; Nandi, Sukumar; Buridipad, Sunil Kumar; Nangi, Gangadhar Bhima Shankar; Meenakshisunderam, Sivakumaran Patent: US2010/48899 A1, 2010 ; Location in patent: Page/Page column 11 ;

~76%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: ASTRAZENECA UK LIMITED Patent: WO2007/7119 A1, 2007 ; Location in patent: Page/Page column 6; 25-26 ; WO 2007/007119 A1

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: AUROBINDO PHARMA LIMITED; MALLELA, Sambhu Prasad Sarma; NANDI, Sukumar; NANGI, Gangadhara Bhima Shankar; ANANTA, Rani; MEENAKSHISUNDERAM, Sivakumaran Patent: WO2010/38124 A1, 2010 ; Location in patent: Page/Page column 19-20 ;

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

~%

METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- Structure

METHANESULFONAM...

CAS#:890028-66-7

Literature: LEK PHARMACEUTICALS D.D.; CASAR, Zdenko; STERK, Damjan; JUKIC, Marko Patent: WO2012/13325 A1, 2012 ;

 Synonyms

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-3-oxo-1-propenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide
N-[4-(4-Fluorophenyl)-6-isopropyl-5-[(1E)-3-oxo-1-propenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide
(2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal
(2E)-3-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}propenal
3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(2E)-propenal
4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-mesylamino)pyrimidin-5-propenal
(E)-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide
trans-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide
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