(S,E)-ETHYL 7-(4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHYLSULFONAMIDO)PYRIMIDIN-5-YL)-5-HYDROXY-3-OXOHEPT-6-ENOATE
Modify Date: 2024-02-01 07:58:10
(S,E)-ETHYL 7-(4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHYLSULFONAMIDO)PYRIMIDIN-5-YL)-5-HYDROXY-3-OXOHEPT-6-ENOATE structure
|
Common Name | (S,E)-ETHYL 7-(4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHYLSULFONAMIDO)PYRIMIDIN-5-YL)-5-HYDROXY-3-OXOHEPT-6-ENOATE | ||
|---|---|---|---|---|
| CAS Number | 901765-36-4 | Molecular Weight | 507.57500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H30FN3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | ethyl (5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-5-hydroxy-3-oxohept-6-enoate |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C24H30FN3O6S |
|---|---|
| Molecular Weight | 507.57500 |
| Exact Mass | 507.18400 |
| PSA | 135.14000 |
| LogP | 4.16920 |
|
~88%
(S,E)-ETHYL 7-(... CAS#:901765-36-4 |
| Literature: ASTRAZENECA UK LIMITED Patent: WO2007/7119 A1, 2007 ; Location in patent: Page/Page column 20 ; WO 2007/007119 A1 |
|
~92%
(S,E)-ETHYL 7-(... CAS#:901765-36-4 |
| Literature: ASTRAZENECA UK LIMITED Patent: WO2008/65410 A1, 2008 ; Location in patent: Page/Page column 27 ; WO 2008/065410 A1 |
|
~64%
(S,E)-ETHYL 7-(... CAS#:901765-36-4 |
| Literature: AUROBINDO PHARMA LIMITED Patent: WO2008/96257 A1, 2008 ; Location in patent: Page/Page column 21-24 ; |
![METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL- structure](https://www.chemsrc.com/caspic/212/890028-66-7.png)
![ethyl 6-(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-methylsulfonylamino]pyrimidin-5-yl]-(5S)-5-(t-butyldimethylsilyloxy)-3-oxoheptenoate structure](https://www.chemsrc.com/caspic/410/1045601-10-2.png)
| Precursor 2 | |
|---|---|
| DownStream 1 | |
CAS#:851443-04-4| 3-keto-5-hydroxy-ethyl rosuvastatin |
| 3-keto-5-hydroxy rosuvastatin ethyl ester |
| (5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-3-oxo-6-heptenoic acid ethyl ester |
| ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-oxo-(5S)-5-hydroxy-(6E)-heptenoate |
| (S,E)-Ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate |
| ethyl 6-(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-methylsulfonylamino]pyrimidin-5-yl]-(5S)-hydroxy-3-oxoheptenoate |
| (S)-trans-ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate |
| ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-oxo-5(S)-hydroxy-6(E)-heptenoate |