890028-66-7

890028-66-7结构式

常用中文名：METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-
常用英文名：METHANESULFONAMIDE,N-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-5-[(1E)-3-OXO-1-PROPEN-1-YL]-2-PYRIMIDINYL]-N-METHYL-
CAS号：890028-66-7
分子式：C₁₈H₂₀FN₃O₃S
分子量：377.43300
发布时间：2017-05-02 19:45:41
更新时间：2024-01-08 16:30:59

英文名	N-[4-(4-fluorophenyl)-5-[(E)-3-oxoprop-1-enyl]-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
中文别名	瑞舒伐他汀钙中间体
英文别名	N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-3-oxo-1-propenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide N-[4-(4-Fluorophenyl)-6-isopropyl-5-[(1E)-3-oxo-1-propenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal (2E)-3-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}propenal 3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(2E)-propenal 4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-mesylamino)pyrimidin-5-propenal (E)-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide trans-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methylmethanesulfonamide

分子式	C₁₈H₂₀FN₃O₃S
分子量	377.43300
精确质量	377.12100
PSA	88.61000
LogP	4.09480

910867-08-2

~96%

890028-66-7

文献：Dandala, Ramesh; Mallela, Sambhu Prasad Sarma; Garimella, Narayan K.A.S.S.; Nandi, Sukumar; Buridipad, Sunil Kumar; Nangi, Gangadhar Bhima Shankar; Meenakshisunderam, Sivakumaran Patent: US2010/48899 A1, 2010 ; Location in patent: Page/Page column 11 ;

901765-35-3

~76%

890028-66-7

文献：ASTRAZENECA UK LIMITED Patent: WO2007/7119 A1, 2007 ; Location in patent: Page/Page column 6; 25-26 ; WO 2007/007119 A1

1220122-72-4

1220122-71-3

68-12-2

890028-66-7

文献：AUROBINDO PHARMA LIMITED; MALLELA, Sambhu Prasad Sarma; NANDI, Sukumar; NANGI, Gangadhara Bhima Shankar; ANANTA, Rani; MEENAKSHISUNDERAM, Sivakumaran Patent: WO2010/38124 A1, 2010 ; Location in patent: Page/Page column 19-20 ;