Pre-骨化三醇PTAD加合物

• 常用名: Pre-骨化三醇PTAD加合物
• 英文名: pre-Calcitriol PTAD Adduct
• CAS号: 86307-44-0
• 分子量: 591.78100
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₅H₄₉N₃O₅
• 熔点: N/A
• 闪点: N/A

Pre-骨化三醇PTAD加合物用途

Impurity C of Calcitriol是Calcitriol的杂质，Calcitriol是维生素D3的活性代谢物，能激活维生素D受体。

Pre-骨化三醇PTAD加合物名称

• 中文名: Pre-骨化三醇PTAD加合物
• 英文名: pre-Calcitriol PTAD Adduct

Pre-骨化三醇PTAD加合物生物活性

• 描述: Impurity C of Calcitriol是Calcitriol的杂质,Calcitriol是维生素D3的活性代谢物,能激活维生素D受体。
• 相关类别:
  信号通路 >> 维生素 D 相关 >> VD/VDR
  研究领域 >> 癌症
• 参考文献:

  [1]. Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004)

  [2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373.

  [3]. Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.

  [4]. Alkharfy KM, Al-Daghri NM, Yakout SM, Ahmed M. Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21.

Pre-骨化三醇PTAD加合物物理化学性质

• 分子式: C₃₅H₄₉N₃O₅
• 分子量: 591.78100
• 精确质量: 591.36700
• PSA: 109.62000
• LogP: 5.05860
• InChIKey: AYDPRRXRNSGAGP-SOWNFDNZSA-N
• SMILES: CC1=C(C2C=C3C(CCC4(C)C3CCC4C(C)CCCC(C)(C)O)n3c(=O)n(-c4ccccc4)c(=O)n32)CC(O)CC1O
• 储存条件: 2-8℃

Pre-骨化三醇PTAD加合物英文别名

• Impurity C of Calcitriol
• Calcitriol Impurity 3