pre-Calcitriol PTAD Adduct
pre-Calcitriol PTAD Adduct structure
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Common Name | pre-Calcitriol PTAD Adduct | ||
|---|---|---|---|---|
| CAS Number | 86307-44-0 | Molecular Weight | 591.78100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H49N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of pre-Calcitriol PTAD AdductImpurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. |
| Name | pre-Calcitriol PTAD Adduct |
|---|---|
| Synonym | More Synonyms |
| Description | Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. |
|---|---|
| Related Catalog | |
| References |
[2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. |
| Molecular Formula | C35H49N3O5 |
|---|---|
| Molecular Weight | 591.78100 |
| Exact Mass | 591.36700 |
| PSA | 109.62000 |
| LogP | 5.05860 |
| Storage condition | 2-8℃ |
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~73%
pre-Calcitriol ... CAS#:86307-44-0 |
| Literature: Vanmaele, L.; Clerq, P. J. de; Vandewalle, M. Tetrahedron, 1985 , vol. 41, # 1 p. 141 - 144 |
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pre-Calcitriol ... CAS#:86307-44-0 |
| Literature: Tetrahedron, , vol. 41, # 1 p. 141 - 144 |
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pre-Calcitriol ... CAS#:86307-44-0 |
| Literature: Tetrahedron, , vol. 41, # 1 p. 141 - 144 |
|
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pre-Calcitriol ... CAS#:86307-44-0 |
| Literature: Tetrahedron, , vol. 41, # 1 p. 141 - 144 |
|
~%
pre-Calcitriol ... CAS#:86307-44-0 |
| Literature: Tetrahedron, , vol. 41, # 1 p. 141 - 144 |
|
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pre-Calcitriol ... CAS#:86307-44-0 |
| Literature: Tetrahedron, , vol. 41, # 1 p. 141 - 144 |
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![(4aR,6aR,7R,9aR,11S)-11-((S)-5-hydroxy-2-methylcyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione structure](https://image.chemsrc.com/caspic/136/86307-41-7.png)
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![(4aR,6aR,7R,9aR,11S)-11-((R)-5-((tert-butyldimethylsilyl)oxy)-2-methyl-3-oxocyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione structure](https://image.chemsrc.com/caspic/028/86323-06-0.png)
CAS#:32222-06-3
CAS#:57102-09-7| Impurity C of Calcitriol |
| Calcitriol Impurity 3 |