... For a general review, see : B. Lythgoe, Chem. Sot. Rev., 2, 449 (1980). SJ Halkes and NP Van Vliet, Rec. Trav. Chim. Pays-Bas, s, 1080 (1969). F. Rolla and D. Landini; Chem. & Ind., 213 (1979). LJ Vanmaele, PJ De Clercq, M. Vandewalle, SJ Halkes, WRM Overbeek, Tetrahedron, 40, 1179 (1984). Absolute proof of the l(S)-configuration in la-hydroxyvitamin D3 (I&) and hence a was obtained by comparison with an authentic sample (see ref. 21.