Tetrahedron

An efficient synthesis of 1α, 25-dihydroxy vitamin D 3

L Vanmaele, PJ De Clercq, M Vandewalle

Index: Vanmaele, L.; Clerq, P. J. de; Vandewalle, M. Tetrahedron, 1985 , vol. 41, # 1 p. 141 - 144

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Citation Number: 29

Abstract

... For a general review, see : B. Lythgoe, Chem. Sot. Rev., 2, 449 (1980). SJ Halkes and NP Van Vliet, Rec. Trav. Chim. Pays-Bas, s, 1080 (1969). F. Rolla and D. Landini; Chem. & Ind., 213 (1979). LJ Vanmaele, PJ De Clercq, M. Vandewalle, SJ Halkes, WRM Overbeek, Tetrahedron, 40, 1179 (1984). Absolute proof of the l(S)-configuration in la-hydroxyvitamin D3 (I&) and hence a was obtained by comparison with an authentic sample (see ref. 21.