表骨化三醇

• 常用名: 表骨化三醇
• 英文名: 1-epi-Calcitriol
• CAS号: 66791-71-7
• 分子量: 416.63600
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₄₄O₃
• 熔点: N/A
• 闪点: N/A

表骨化三醇用途

Impurity B of Calcitriol是Calcitriol的杂质,Calcitriol是维生素D3的活性代谢物,能激活维生素D受体。

表骨化三醇名称

• 中文名: 表骨化三醇
• 英文名: [3H]-1,25-Dihydroxyvitamin D3
• 中文别名: 1-表钙三醇 | 1beta,25-二羟基维他命-D3

表骨化三醇生物活性

• 描述: Impurity B of Calcitriol是Calcitriol的杂质,Calcitriol是维生素D3的活性代谢物,能激活维生素D受体。
• 相关类别:
  信号通路 >> 维生素 D 相关 >> VD/VDR
  研究领域 >> 癌症
• 参考文献:

  [1]. Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004)

  [2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373.

  [3]. Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.

  [4]. Alkharfy KM, Al-Daghri NM, Yakout SM, Ahmed M. Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21.

表骨化三醇物理化学性质

• 分子式: C₂₇H₄₄O₃
• 分子量: 416.63600
• 精确质量: 416.32900
• PSA: 60.69000
• LogP: 5.70470
• InChIKey: GMRQFYUYWCNGIN-BJBFBDRLSA-N
• SMILES: C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)(C)O)CC(O)CC1O
• 储存条件: 2-8℃

表骨化三醇英文别名

• IMpurity B of Calcitriol
• EPI-CALCITRIOL
• 1-epi-Calcitriol
• 1-Epicalcitriol
• Calcitriol Impurity 2