5-乙烯基尿嘧啶

更新时间:2024-01-09 18:38:07

5-乙烯基尿嘧啶结构式
5-乙烯基尿嘧啶结构式
品牌特惠专场
常用名 5-乙烯基尿嘧啶 英文名 5-vinyluracil
CAS号 37107-81-6 分子量 138.12400
密度 1.332g/cm3 沸点 N/A
分子式 C6H6N2O2 熔点 >300ºC (dec.)(lit.)
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

 5-乙烯基尿嘧啶名称

中文名 5-乙烯尿嘧啶
英文名 5-ethenyl-1H-pyrimidine-2,4-dione
中文别名 5-乙烯基尿嘧啶 | 5-乙烯基-1H-嘧啶-2,4-二酮
英文别名 更多

 5-乙烯基尿嘧啶物理化学性质

密度 1.332g/cm3
熔点 >300ºC (dec.)(lit.)
分子式 C6H6N2O2
分子量 138.12400
精确质量 138.04300
PSA 65.72000
外观性状 Powder
折射率 1.606
储存条件 -20°C Freezer
计算化学

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:2

3.氢键受体数量:2

4.可旋转化学键数量:1

5.互变异构体数量:12

6.拓扑分子极性表面积58.2

7.重原子数量:10

8.表面电荷:0

9.复杂度:230

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

 5-乙烯基尿嘧啶安全信息

符号 GHS07
GHS07
信号词 Warning
危害声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xi: Irritant;
风险声明 (欧洲) 36/37/38
安全声明 (欧洲) 26-36/37
危险品运输编码 NONH for all modes of transport
WGK德国 3
海关编码 2933599090

 5-乙烯基尿嘧啶海关

海关编码 2933599090
中文概述 2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 5-乙烯基尿嘧啶文献3

更多文献
A method for the rapid preparation of 5-vinyluracil in high yield.

Nucleic Acids Res. 1(1) , 105-7, (1974)

A method for the rapid preparation of the thymineanalogue, 5-vinyluracil, in 83% yield from 5-(1-hydroxyethyl)uracil via the methanesulphonyl ester is reported.

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

Bioorg. Med. Chem. Lett. 13(5) , 867-72, (2003)

A series of tumor-activated prodrugs of the inhibitors of dihydropyrimidine dehydrogenase (DPD), an enzyme catabolizing 5-fluorouracil (5-FU: 4g), has been designed and synthesized. RO0094889 (11c) is...

Incorporation of 5-substituted uracil derivatives into nucleic acids. The isolation and gamma-radiation-sensitivity of bacteriophage T3 containing the thymine analogue 5-vinyluracil.

Biochem. J. 187(1) , 257-60, (1980)

Bacteriophage T3 was produced in a form that contained 32% of its normal DNA thymine residues replaced with 5-vinyluracil residues by infecting a thymine-requiring strain of Escherichia coli with phag...

 5-乙烯基尿嘧啶英文别名

5-ethenyluracil
5-vinyl-1H-pyrimidine-2,4-dione
MFCD00913267
5-ethenyl-2,4(1H,3H)-pyrimidinedione
5-Vinyl-uracil
5-ethenylpyrimidine-2,4-diol