茚达特罗

• 常用名: 茚达特罗
• 英文名: Indacaterol
• CAS号: 312753-06-3
• 分子量: 392.49100
• 密度: 1.27
• 沸点: N/A
• 分子式: C₂₄H₂₈N₂O₃
• 熔点: N/A
• 闪点: N/A

茚达特罗用途

Indacaterol(Onbrez; Arcapta)是超长效β-肾上腺素受体激动剂。

茚达特罗名称

• 中文名: 茚达特罗
• 英文名: indacaterol

茚达特罗生物活性

• 描述: Indacaterol(Onbrez; Arcapta)是超长效β-肾上腺素受体激动剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Battram, C., et al., In vitro and in vivo pharmacological characterization of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-o ne (indacaterol), a novel inhaled beta(2) adrenoceptor agonist with a 24-h duration of action.

  [2]. Sturton, R.G., et al., Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices. J Pharmacol Exp Ther, 2008. 324(1): p. 270-5.

茚达特罗物理化学性质

• 密度: 1.27
• 分子式: C₂₄H₂₈N₂O₃
• 分子量: 392.49100
• 精确质量: 392.21000
• PSA: 85.35000
• LogP: 3.53980
• 储存条件: 2-8°C

茚达特罗英文别名

• Arcapta
• 2(1H)-QUINOLINONE,5-[(1R)-2-[(5,6-DIETHYL-2,3-DIHYDRO-1H-INDEN-2-YL)AMINO]-1-HYDROXYETHYL]-8-HYDROXY-
• 5-{(1R)-2-((5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl}-8-hydroxyquinolin-2(1H)-one
• [3H]-Indacaterol
• 2(1H)-Quinolinone, 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-
• Indacaterol
• 5-{(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl}-8-hydroxy-2(1H)-quinolinone
• Onbrez