SDZ 220-581铵盐

• 常用名: SDZ 220-581铵盐
• 英文名: SDZ 220-581 Ammonium salt
• CAS号: 179411-94-0
• 分子量: 386.767
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₂₀ClN₂O₅P
• 熔点: N/A
• 闪点: N/A

SDZ 220-581铵盐用途

SDZ 220-581铵盐是NMDA谷氨酸受体竞争性拮抗剂。

SDZ 220-581铵盐名称

• 中文名: SDZ 220-581铵盐
• 英文名: SDZ 220-581 Ammonium salt

SDZ 220-581铵盐生物活性

• 描述: SDZ 220-581铵盐是NMDA谷氨酸受体竞争性拮抗剂。
• 相关类别:
  信号通路 >> 跨膜转运 >> iGluR
  信号通路 >> 神经信号通路 >> iGluR
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Gilmour G, Broad LM, Wafford KA, In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat. Neuropharmacology. 2013 Jan;64:224-39.

  [2]. Urwyler S, Campbell E, Fricker G, Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists--II. Pharmacological characterization in vivo. Neuropharmacology. 1996 Jun;35(6):655-69.

  [3]. Bakshi VP, Tricklebank M, Neijt HC, Disruption of prepulse inhibition and increases in locomotor activity by competitive N-methyl-D-aspartate receptor antagonists in rats. J Pharmacol Exp Ther. 1999 Feb;288(2):643-52.

  [4]. Linderholm K, Powell S, Olsson E, Role of the NMDA-receptor in Prepulse Inhibition in the Rat. Int J Tryptophan Res. 2010;3:1-12.

SDZ 220-581铵盐物理化学性质

• 分子式: C₁₆H₂₀ClN₂O₅P
• 分子量: 386.767
• 精确质量: 386.079834
• InChIKey: JSKZYMJZKPLCNJ-UHFFFAOYSA-N
• SMILES: N.NC(Cc1cc(CP(=O)(O)O)cc(-c2ccccc2Cl)c1)C(=O)O
• 储存条件: 2-8℃

SDZ 220-581铵盐英文别名

• SDZ 220-581 (Ammonium salt)