2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺

更新时间:2024-01-08 17:33:44

2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺结构式
2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺结构式
品牌特惠专场
常用名 2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺 英文名 SCH 58261
CAS号 160098-96-4 分子量 345.35800
密度 1.54g/cm3 沸点 N/A
分子式 C18H15N7O 熔点 N/A
MSDS 美版 闪点 N/A

 用途


SCH58261是adenosine A2A receptor竞争性的拮抗剂。

 名称

中文名 2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺
英文名 2-(2-furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
英文别名 更多

 物理化学性质

密度 1.54g/cm3
分子式 C18H15N7O
分子量 345.35800
精确质量 345.13400
PSA 100.06000
LogP 3.14010
折射率 1.807
储存条件 2-8°C

 安全信息

个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码 NONH for all modes of transport
海关编码 2934999090

 合成线路

~20%

2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺结构式

2-(2-呋喃基)-7-(2-...

160098-96-4

文献:Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171

~%

2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺结构式

2-(2-呋喃基)-7-(2-...

160098-96-4

文献:Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171

~%

2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺结构式

2-(2-呋喃基)-7-(2-...

160098-96-4

文献:Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171

~%

2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺结构式

2-(2-呋喃基)-7-(2-...

160098-96-4

文献:Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171

 海关

海关编码 2934999090
中文概述 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 文献9

更多文献
On the role of adenosine (A)₂A receptors in cocaine-induced reward: a pharmacological and neurochemical analysis in rats.

Psychopharmacol. Ser. 232(2) , 421-35, (2015)

Several studies have suggested the inhibitory control of adenosine (A)2A receptor stimulation in cocaine-induced behavioral actions.A combination of systemic or local drug injections and in vivo neuro...

Endothelial dysfunction impairs vascular neurotransmission in tail arteries.

Neurochem. Int. 80 , 7-13, (2015)

The present study intends to clarify if endothelium dysfunction impairs vascular sympathetic neurotransmission. Electrically-evoked tritium overflow (100 pulses/5 Hz) was evaluated in arteries (intact...

Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure.

J. Neuroinflammation 12 , 115, (2015)

Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a degenerative disease characterized by the loss of retinal ganglion cells (RGCs). There is clinical and experimental evidence ...

 英文别名

7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
SCH58261
SCH 58261
品牌现货直购
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2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺生产厂家

2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺价格