4'-氯地西泮

更新时间：2024-01-03 21:18:12

4'-氯地西泮结构式	常用名	4'-氯地西泮	英文名	4'-Chlorodiazepam
	CAS号	14439-61-3	分子量	319.18500
	密度	1.35g/cm3	沸点	517.1ºC at 760mmHg
	分子式	C₁₆H₁₂Cl₂N₂O	熔点	160-163ºC
	MSDS	中文版美版	闪点	266.6ºC
	符号	GHS07	信号词	Warning

4'-氯地西泮用途

A potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR).

中文名	4'-氯地西泮
英文名	4'-Chlorodiazepam
英文别名	更多

密度	1.35g/cm3
沸点	517.1ºC at 760mmHg
熔点	160-163ºC
分子式	C₁₆H₁₂Cl₂N₂O
分子量	319.18500
闪点	266.6ºC
精确质量	318.03300
PSA	32.67000
LogP	3.30780
蒸汽压	8.43E-11mmHg at 25°C
折射率	1.647
储存条件	2-8℃，干燥，密闭

4'-氯地西泮毒性英文版

符号	GHS07
信号词	Warning
危害声明	H302
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xn: Harmful;
风险声明 (欧洲)	22
危险品运输编码	UN 2811
RTECS号	DF0500000
包装等级	III
危险类别	6.1(b)
海关编码	2933990090

N-(4-chloro-2-(...

99833-83-7

~81%

4'-氯地西泮

14439-61-3

文献：Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

N-(4-chloro-2-(...

99833-82-6

~94%

4'-氯地西泮

14439-61-3

文献：Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

7-chloro-1,3-di...

5571-60-8

甲基碘

74-88-4

~36%

4'-氯地西泮

14439-61-3

文献：Cortes, Eduardo Cortes; Martinez, Isidro Ebromares; Mellado, Olivia Garcia Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 6 p. 1189 - 1194

5-Chloro-3-(4-c...

724-07-2

4'-氯地西泮

14439-61-3

文献：Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

5,4'-dichloro-2...

78961-59-8

4'-氯地西泮

14439-61-3

文献：Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

对硝基氯苯

100-00-5

4'-氯地西泮

14439-61-3

文献：Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

对氯苯乙腈

140-53-4

4'-氯地西泮

14439-61-3

文献：Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

4'-氯地西泮上游产品 6
CAS号5571-60-8 7-chloro-1,3-di... CAS号74-88-4 甲基碘 CAS号724-07-2 5-Chloro-3-(4-c... CAS号78961-59-8 5,4'-dichloro-2...
CAS号100-00-5 对硝基氯苯 CAS号140-53-4 对氯苯乙腈
4'-氯地西泮下游产品 0

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.

J. Med. Chem. 49 , 5845-8, (2006)

Cultured rat astrocytes and C6 rat glioma were used as a differential screen for a variety of 1,2,3,4-tetrahydroisoquinoline (THI) derivatives. Compound 1 [1-(biphenyl-4-ylmethyl)-1,2,3,4-tetrahydrois...

Investigation into mechanisms mediating the inhibitory effect of 1,4-benzodiazepines on mast cells by gene expression profiling.

Life Sci. 92(6-7) , 345-51, (2013)

This study aims to identify by a molecular genetic approach potential targets in mast cells at which 1,4-benzodiazepines may cause their inhibitory effect on mast cell activity.Gene expression analyse...

Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis.

Biochem. Pharmacol. 97 , 99-110, (2015)

As a major regulator in obesity and its associated metabolic complications, the proper functioning of adipocytes is crucial for health maintenance, thus serving as an important target for the developm...

Chlorodiazepam

4'-Chlorodiazepam

7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one

Ro-5-4864

7-chloro-5-(4-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one