4'-Chlorodiazepam
4'-Chlorodiazepam structure
|
Common Name | 4'-Chlorodiazepam | ||
|---|---|---|---|---|
| CAS Number | 14439-61-3 | Molecular Weight | 319.18500 | |
| Density | 1.35g/cm3 | Boiling Point | 517.1ºC at 760mmHg | |
| Molecular Formula | C16H12Cl2N2O | Melting Point | 160-163ºC | |
| MSDS | Chinese USA | Flash Point | 266.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 4'-ChlorodiazepamA potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR). |
| Name | 4'-Chlorodiazepam |
|---|---|
| Synonym | More Synonyms |
| Density | 1.35g/cm3 |
|---|---|
| Boiling Point | 517.1ºC at 760mmHg |
| Melting Point | 160-163ºC |
| Molecular Formula | C16H12Cl2N2O |
| Molecular Weight | 319.18500 |
| Flash Point | 266.6ºC |
| Exact Mass | 318.03300 |
| PSA | 32.67000 |
| LogP | 3.30780 |
| Vapour Pressure | 8.43E-11mmHg at 25°C |
| Index of Refraction | 1.647 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 22 |
| RIDADR | UN 2811 |
| RTECS | DF0500000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
J. Med. Chem. 49 , 5845-8, (2006) Cultured rat astrocytes and C6 rat glioma were used as a differential screen for a variety of 1,2,3,4-tetrahydroisoquinoline (THI) derivatives. Compound 1 [1-(biphenyl-4-ylmethyl)-1,2,3,4-tetrahydrois... |
|
|
Investigation into mechanisms mediating the inhibitory effect of 1,4-benzodiazepines on mast cells by gene expression profiling.
Life Sci. 92(6-7) , 345-51, (2013) This study aims to identify by a molecular genetic approach potential targets in mast cells at which 1,4-benzodiazepines may cause their inhibitory effect on mast cell activity.Gene expression analyse... |
|
|
Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis.
Biochem. Pharmacol. 97 , 99-110, (2015) As a major regulator in obesity and its associated metabolic complications, the proper functioning of adipocytes is crucial for health maintenance, thus serving as an important target for the developm... |
| Chlorodiazepam |
| 4'-Chlorodiazepam |
| 7-Chloro-5-(4-chlorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one |
| Ro-5-4864 |
| 7-chloro-5-(4-chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one |