Synthesis of 7-chloro-5-(4-chlorophenyl)-1-methyl-1, 3-dihydro-1, 4-benzodiazepin-2-one

Z Vejdělek, Z Polívka, M Protiva

Index: Vejdelek; Polivka; Protiva Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 5 p. 1064 - 1069

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Citation Number: 5

Abstract

Abstract The synthesis of the title compound II was carried out from 5-chloro-3-(4- chlorophenyl)-2, 1-benzisoxazole (III) by two methods proceeding via new intermediates V and VI. 5-(2-Fluorophenyl)-1, 3-dihydro-1, 4-benzodiazepin-2-one (VII) was synthesized from 2-amino-2'-fluorobenzophenone via VIII.