希伯胺结构式
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常用名 | 希伯胺 | 英文名 | Xipamide |
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CAS号 | 14293-44-8 | 分子量 | 354.809 | |
密度 | 1.5±0.1 g/cm3 | 沸点 | N/A | |
分子式 | C15H15ClN2O4S | 熔点 | 255-256ºC | |
MSDS | 中文版 美版 | 闪点 | N/A | |
符号 |
GHS07 |
信号词 | Warning |
希伯胺用途Xipamide 是一种磺胺类利尿剂。Xipamide 是一种能选择性抑制阴离子交换剂 (AE) 的降压药。 |
中文名 | 利多速尿 |
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英文名 | 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide |
中文别名 | 5-(氨基磺酰基)-4-氯-N-(2,6-二甲基苯基)-2-羟基苯甲酰胺 | 希伯胺 |
英文别名 | 更多 |
描述 | Xipamide 是一种磺胺类利尿剂。Xipamide 是一种能选择性抑制阴离子交换剂 (AE) 的降压药。 |
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相关类别 | |
参考文献 |
密度 | 1.5±0.1 g/cm3 |
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熔点 | 255-256ºC |
分子式 | C15H15ClN2O4S |
分子量 | 354.809 |
精确质量 | 354.044098 |
PSA | 117.87000 |
LogP | 2.50 |
折射率 | 1.653 |
储存条件 | Refrigerator |
计算化学 | 1.疏水参数计算参考值(XlogP):2.9 2.氢键供体数量:3 3.氢键受体数量:5 4.可旋转化学键数量:3 5.互变异构体数量:7 6.拓扑分子极性表面积:118 7.重原子数量:23 8.表面电荷:0 9.复杂度:526 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
符号 |
GHS07 |
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信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
危害码 (欧洲) | Xi |
风险声明 (欧洲) | 36/37/38 |
安全声明 (欧洲) | 26 |
危险品运输编码 | NONH for all modes of transport |
海关编码 | 2935009090 |
海关编码 | 2935009090 |
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中文概述 | 2935009090 其他磺(酰)胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0% |
申报要素 | 品名, 成分含量, 用途 |
Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Clinicopharmacological reappraisal of the potency of diuretics.
Cardiovasc. Drugs Ther. 7 Suppl 1 , 23-8, (1993) From a clinicopharmacological standpoint, the urinary excretory potency of diuretics should be assessed comparatively on the basis of the changes in 24-hour natriuresis, with respect to 24-hour natriu... |
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Bioavailability study of triamterene and xipamide using urinary pharmacokinetic data following single oral dose of each drug or their combination.
J. Pharm. Biomed. Anal. 61 , 78-85, (2012) An efficient chromatographic method for the simultaneous determination of triamterene (TRI) and xipamide (XIP) in urine samples, based on high performance liquid chromatography with photodiode array d... |
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Spectrophotometric and spectrodensitometric determination of triamterene and xipamide in pure form and in pharmaceutical formulation.
Drug Test. Anal. 2(3) , 113-21, (2010) Sensitive and validated UV-spectrophotometric, chemometric and TLC-densitometric methods were developed for determination of triamterene (TRM) and xipamide (XIP) in their binary mixture, formulated fo... |
Benzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy- |
Xipamide |
EINECS 238-216-4 |
Aquaphor |
4-Chloro-2',6'-dimethyl-5-sulfamoylsalicylanilide |
4-Chloro-5-sulfamylsalicyloyl-2',6'-dimethylanilide |
Xipamid |
5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide |
4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide |
Zipix |
Aquaphoril |
4-chloro-2',6-dimethyl-5-sulfamoylsalicylanilide |
Diurexan |
5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxybenzamide |