Xipamide structure
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Common Name | Xipamide | ||
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CAS Number | 14293-44-8 | Molecular Weight | 354.809 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C15H15ClN2O4S | Melting Point | 255-256ºC | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of XipamideXipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1]. |
Name | 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide |
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Synonym | More Synonyms |
Description | Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1]. |
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Related Catalog | |
References |
Density | 1.5±0.1 g/cm3 |
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Melting Point | 255-256ºC |
Molecular Formula | C15H15ClN2O4S |
Molecular Weight | 354.809 |
Exact Mass | 354.044098 |
PSA | 117.87000 |
LogP | 2.50 |
Index of Refraction | 1.653 |
Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Phrases | 36/37/38 |
Safety Phrases | 26 |
RIDADR | NONH for all modes of transport |
HS Code | 2935009090 |
HS Code | 2935009090 |
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Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Clinicopharmacological reappraisal of the potency of diuretics.
Cardiovasc. Drugs Ther. 7 Suppl 1 , 23-8, (1993) From a clinicopharmacological standpoint, the urinary excretory potency of diuretics should be assessed comparatively on the basis of the changes in 24-hour natriuresis, with respect to 24-hour natriu... |
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Bioavailability study of triamterene and xipamide using urinary pharmacokinetic data following single oral dose of each drug or their combination.
J. Pharm. Biomed. Anal. 61 , 78-85, (2012) An efficient chromatographic method for the simultaneous determination of triamterene (TRI) and xipamide (XIP) in urine samples, based on high performance liquid chromatography with photodiode array d... |
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Spectrophotometric and spectrodensitometric determination of triamterene and xipamide in pure form and in pharmaceutical formulation.
Drug Test. Anal. 2(3) , 113-21, (2010) Sensitive and validated UV-spectrophotometric, chemometric and TLC-densitometric methods were developed for determination of triamterene (TRM) and xipamide (XIP) in their binary mixture, formulated fo... |
Benzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy- |
Xipamide |
EINECS 238-216-4 |
Aquaphor |
4-Chloro-2',6'-dimethyl-5-sulfamoylsalicylanilide |
4-Chloro-5-sulfamylsalicyloyl-2',6'-dimethylanilide |
Xipamid |
5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide |
4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide |
Zipix |
Aquaphoril |
4-chloro-2',6-dimethyl-5-sulfamoylsalicylanilide |
Diurexan |
5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxybenzamide |