双醋瑞因; 二乙酰大黄酸; 二乙酰二氢蒽羧酸结构式
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常用名 | 双醋瑞因; 二乙酰大黄酸; 二乙酰二氢蒽羧酸 | 英文名 | Diacerein |
|---|---|---|---|---|
| CAS号 | 13739-02-1 | 分子量 | 368.294 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 631.5±55.0 °C at 760 mmHg | |
| 分子式 | C19H12O8 | 熔点 | 217-2180C | |
| MSDS | N/A | 闪点 | 231.8±25.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
用途Diacerein是白介素-1β抑制剂,是慢效的蒽醌类化合物。 |
| 中文名 | 1,8-二乙酰基-3-羧基蒽醌 |
|---|---|
| 英文名 | 1,8-Diacetoxy-3-carboxyanthraquinone |
| 中文别名 | 双醋瑞因 | 双醋瑞因DIACEREIN | 安必丁 | 4,5-二乙酰-9,10-二氧-2-蒽羧酸 | 4,5-二乙酰氧基蒽醌-2-羧酸 | 二乙酰大黄酸 |
| 英文别名 | 更多 |
| 密度 | 1.5±0.1 g/cm3 |
|---|---|
| 沸点 | 631.5±55.0 °C at 760 mmHg |
| 熔点 | 217-2180C |
| 分子式 | C19H12O8 |
| 分子量 | 368.294 |
| 闪点 | 231.8±25.0 °C |
| 精确质量 | 368.053223 |
| PSA | 124.04000 |
| LogP | 1.99 |
| 外观性状 | 固体;Light yellow to Amber to Dark green powder to crystal |
| 蒸汽压 | 0.0±1.9 mmHg at 25°C |
| 折射率 | 1.634 |
| 储存条件 | Refrigerator |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H315-H319-H335 |
| 警示性声明 | P305 + P351 + P338 |
| 危害码 (欧洲) | Xi |
| 风险声明 (欧洲) | 36/37/38 |
| 安全声明 (欧洲) | 26-36 |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
| RTECS号 | CB8781000 |
| 海关编码 | 2918990090 |
| 双醋瑞因; 二乙酰大黄酸; 二乙酰二氢蒽羧酸上游产品 8 | |
|---|---|
| 双醋瑞因; 二乙酰大黄酸; 二乙酰二氢蒽羧酸下游产品 2 | |
| 海关编码 | 2918990090 |
|---|---|
| 中文概述 | 2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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[Diacerein].
Ann. Ital. Med. Int. 1(2) , 172-4, (1986)
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[Efficacy of diacerein on the symptoms and radiographic progression of osteoarthritis].
Presse Med. 31(39 Pt 2) , 4S13-5, (2002) SYMPTOMATIC EFFECTS OF DIACEREIN: Data obtained from several clinical trials have demonstrated that relief of joint pain obtained with the interleukin-1 inhibitor diacerein is comparable with that obs... |
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Diacerein as a disease-modulating agent in osteoarthritis.
Curr. Rheumatol. Rep. 3(6) , 479-83, (2001) This paper reviews the most recent clinical and experimental studies on diacerein, both of which are under investigation. Diacerein could be a disease-modulating agent in osteoarthritis because struct... |
| 4,5-Diacetoxy-9,10-dioxo-9,10-dihydro-2-anthracenecarboxylic acid |
| DIACERHEIN |
| MFCD00468030 |
| DIACETYL RHEIN |
| 2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo- |
| Fisiodar |
| 4,5-diacetylrhein |
| Rhein Diacetate |
| 4,5-diacetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid |
| SF 277 |
| rhein,diacetate |
| Diacerein |
| 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic Acid |
| artrodar |
| Diacereine |
| EINECS 237-310-2 |
| DAR |
| 4,5-Diacetoxyanthraquinone-2-carboxylic Acid |
| diacetylrhein |
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