MC 1046

• 常用名: MC 1046
• 英文名: MC 1046
• CAS号: 126860-83-1
• 分子量: 410.589
• 密度: 1.1±0.1 g/cm3
• 沸点: 584.2±50.0 °C at 760 mmHg
• 分子式: C₂₇H₃₈O₃
• 熔点: N/A
• 闪点: 321.1±26.6 °C

MC 1046用途

MC 1046(Impurity A of Calcipotriol)是钙泊三醇的杂质,钙泊三醇是1,25-Dihydroxyvitamin D3类似物。

MC 1046名称

• 中文名: MC 1046
• 英文名: MC 1046

MC 1046生物活性

• 描述: MC 1046(Impurity A of Calcipotriol)是钙泊三醇的杂质,钙泊三醇是1,25-Dihydroxyvitamin D3类似物。
• 相关类别:
  信号通路 >> 维生素 D 相关 >> VD/VDR
  研究领域 >> 癌症
• 参考文献:

  [1]. Binderup (1993) Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: effects on cell growth regulation in vitro and calcium metabolism in vivo. Pharmacol.Toxicol. 72 240.

  [2]. Knutson et al (1997) Pharmacokinetics and systemic effect on calcium homeostasis of 1a,24-dihydroxyvitamin D2 in rats. Biochem.Pharmacol. 53 829.

  [3]. Wietrzyk et al (2007) Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anticancer Drugs 18 447.111

  [4]. P.J. Marie, D. Connes, M. Hott, L. Miravet. Comparative effects of a novel Vitamin D Analogue MC-903 and 1,25-dihydroxyvitamin D3 on alkaline phosphatase activity, osteocalcin and DNA synthesis by human osteoblastic cells in culture. Bone. Volume 11, Issue 3, 1990, Pages 171-179

MC 1046物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 584.2±50.0 °C at 760 mmHg
• 分子式: C₂₇H₃₈O₃
• 分子量: 410.589
• 闪点: 321.1±26.6 °C
• 精确质量: 410.282104
• LogP: 4.95
• 蒸汽压: 0.0±3.7 mmHg at 25°C
• 折射率: 1.574
• 储存条件: 2-8℃

MC 1046英文别名

• 2-Penten-1-one, 1-cyclopropyl-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-, (2E,4R)-
• G70BS4HF9Z
• MFCD00872035
• MC-1046
• (1S,3R,5Z,7E,22E)-1,3-Dihydroxy-26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraen-24-one