β-Interleukin I (163-171), human

更新时间：2025-08-27 10:39:20

β-Interleukin I (163-171), human结构式	常用名	β-Interleukin I (163-171), human	英文名	β-Interleukin I (163-171), human
	CAS号	106021-96-9	分子量	1004.99000
	密度	1.419g/cm3	沸点	1682.6ºC at 760mmHg
	分子式	C₃₉H₆₄N₁₂O₁₉	熔点	N/A
	MSDS	N/A	闪点	971.4ºC

β-Interleukin I (163-171), human用途

β-白细胞介素I(163-171),人,人IL-1β肽的免疫刺激片段,是T细胞激活剂。β-白细胞介素I(163-171),人不是IL-1β的IL-1R结合域。β-白细胞介素I(163-171),人是一种有效的佐剂,在多种实验中增强免疫反应。情况[1][3][4]。

英文名	val-gln-gly-glu-glu-ser-asn-asp-lys
英文别名	更多

描述	β-白细胞介素I(163-171),人,人IL-1β肽的免疫刺激片段,是T细胞激活剂。β-白细胞介素I(163-171),人不是IL-1β的IL-1R结合域。β-白细胞介素I(163-171),人是一种有效的佐剂,在多种实验中增强免疫反应。情况[1][3][4]。
相关类别	信号通路 >> 其他 >> 其他研究领域 >> 炎症/免疫
体外研究	β-白介素I(163-171),人(12.5-400μg/mL,72小时)刺激小鼠胸腺细胞增殖[6]。
体内研究	β-白细胞介素I(163-171),人(50μg,每天,BALB/c小鼠模型的免疫原性较差的纤维肉瘤(CE-2))诱导了一致但有限的肿瘤生长抑制[2]。β-白细胞介素I(163-171),人(1μmol/kg,静脉注射)与T依赖性抗原SRBC一起增加对抗原的主要免疫应答[3]。
参考文献	[1]. Nencioni L, et al. In vivo immunostimulating activity of the 163-171 peptide of human IL-1 beta. J Immunol. 1987 Aug 1;139(3):800-4. [2]. Forni G, et al. Ability of a nonapeptide of the human IL-1 beta to recruit anti-tumor reactivity in recipient mice. J Immunol. 1989 Jan 15;142(2):712-8. [3]. Boraschi D, , et al. In vivo stimulation and restoration of the immune response by the noninflammatory fragment 163-171 of human interleukin 1 beta. J Exp Med. 1988 Aug 1;168(2):675-86. [4]. Tagliabue, A., et al. (1997). Interleukin 1 and Its Synthetic Peptide 163–171 as Vaccine Adjuvants. Vaccine Design pp 167-173. [5]. Boraschi D, et al. Binding and internalization of the 163-171 fragment of human IL-1 beta. Cytokine. 1992 May;4(3):201-4. [6]. Bajpai K, et al. Immunomodulating activity of analogs of noninflammatory fragment 163-171 of human interleukin-1beta. Immunopharmacology. 1998 Jan;38(3):237-45.

密度	1.419g/cm3
沸点	1682.6ºC at 760mmHg
分子式	C₃₉H₆₄N₁₂O₁₉
分子量	1004.99000
闪点	971.4ºC
精确质量	1004.44000
PSA	540.45000
蒸汽压	0mmHg at 25°C
折射率	1.573
储存条件	-20°C

WGK德国	3

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β-Interleukin I (163-171)