克拉珠利

更新时间：2025-08-27 07:10:17

克拉珠利结构式	常用名	克拉珠利	英文名	Clazuril
	CAS号	101831-36-1	分子量	373.19300
	密度	1.48g/cm3	沸点	N/A
	分子式	C₁₇H₁₀Cl₂N₄O₂	熔点	196.8°
	MSDS	N/A	闪点	N/A

克拉珠利用途

Clazuril(R62690)对两种艾美耳球虫的无性和性发育阶段都有杀球虫作用,导致生命周期完全中断[1]。

中文名	克拉珠利
英文名	2-[2-chloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]-2-(4-chlorophenyl)acetonitrile
英文别名	更多

描述	Clazuril(R62690)对两种艾美耳球虫的无性和性发育阶段都有杀球虫作用,导致生命周期完全中断[1]。
相关类别	研究领域 >> 感染
体内研究	克拉珠利(2.5毫克/鸽)可迅速抑制卵囊排泄,但在治疗20天后,在粪便中再次观察到卵囊。治疗3至5周后,卵囊再次出现在粪便中,这一事实可能只能通过内源性阶段的持续性来解释,内源性阶段在治疗期间不受影响,而不是通过再次感染[2]。
参考文献	[1]. W Coussement, et al. Action of the anticoccidial clazuril on the endogenous stages of Eimeria labbeana and E columbarum in experimentally infected pigeons. Res Vet Sci. 1988 Jul;45(1):117-9. [2]. J Vercruysse, et al. Efficacy of toltrazuril and clazuril against experimental infections with Eimeria labbeana and E. columbarum in racing pigeons. Avian Dis. Jan-Mar 1990;34(1):73-9.

密度	1.48g/cm3
熔点	196.8°
分子式	C₁₇H₁₀Cl₂N₄O₂
分子量	373.19300
精确质量	372.01800
PSA	91.54000
LogP	2.88308
折射率	1.692

2-[3-chloro-4-[...

103337-60-6

~11%

克拉珠利

101831-36-1

文献：Janssen Pharmaceutica N.V. Patent: US4631278 A1, 1986 ;

Efficacy of selected coccidiostats in sandhill cranes (Grus canadensis) following challenge.

J. Zoo Wildl. Med. 36(3) , 391-400, (2005)

The anticoccidial efficacy of amprolium, clazuril, and monensin were studied in sandhill cranes (Grus canadensis) infected with a mixture of Eimeria spp. oocysts. Five groups of four 1-day-old sandhil...

Action of the anticoccidial clazuril on the endogenous stages of Eimeria labbeana and E columbarum in experimentally infected pigeons.

Res. Vet. Sci. 45(1) , 117-9, (1988)

Racing pigeons were artificially infected with a mixed inoculum of Eimeria labbeana (85 per cent) and E columbarum (15 per cent) and treated orally with 2.5 mg clazuril either on day 1, 2, 3, 4, 5, 6 ...

Efficacy of toltrazuril and clazuril against experimental infections with Eimeria labbeana and E. columbarum in racing pigeons.

Avian Dis. 34(1) , 73-9, (1990)

The efficacy of toltrazuril in comparison with clazuril on heavy experimental Eimeria labbeana and E. columbarum infections in pigeons was investigated. The minimum required dose of toltrazuril to com...

CLAZURIL

Clazurilum [Latin]

[2-chloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3h)-yl)phenyl](4-chlorophenyl)acetonitrile

Clazurilo [Spanish]

Clazuril (USAN/INN)

Clazurilo

Clazurilum