克拉珠利结构式
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常用名 | 克拉珠利 | 英文名 | Clazuril |
|---|---|---|---|---|
| CAS号 | 101831-36-1 | 分子量 | 373.19300 | |
| 密度 | 1.48g/cm3 | 沸点 | N/A | |
| 分子式 | C17H10Cl2N4O2 | 熔点 | 196.8° | |
| MSDS | N/A | 闪点 | N/A |
克拉珠利用途Clazuril(R62690)对两种艾美耳球虫的无性和性发育阶段都有杀球虫作用,导致生命周期完全中断[1]。 |
| 中文名 | 克拉珠利 |
|---|---|
| 英文名 | 2-[2-chloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]-2-(4-chlorophenyl)acetonitrile |
| 英文别名 | 更多 |
| 描述 | Clazuril(R62690)对两种艾美耳球虫的无性和性发育阶段都有杀球虫作用,导致生命周期完全中断[1]。 |
|---|---|
| 相关类别 | |
| 体内研究 | 克拉珠利(2.5毫克/鸽)可迅速抑制卵囊排泄,但在治疗20天后,在粪便中再次观察到卵囊。治疗3至5周后,卵囊再次出现在粪便中,这一事实可能只能通过内源性阶段的持续性来解释,内源性阶段在治疗期间不受影响,而不是通过再次感染[2]。 |
| 参考文献 |
| 密度 | 1.48g/cm3 |
|---|---|
| 熔点 | 196.8° |
| 分子式 | C17H10Cl2N4O2 |
| 分子量 | 373.19300 |
| 精确质量 | 372.01800 |
| PSA | 91.54000 |
| LogP | 2.88308 |
| 折射率 | 1.692 |
|
~11%
克拉珠利 101831-36-1 |
| 文献：Janssen Pharmaceutica N.V. Patent: US4631278 A1, 1986 ; |
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Efficacy of selected coccidiostats in sandhill cranes (Grus canadensis) following challenge.
J. Zoo Wildl. Med. 36(3) , 391-400, (2005) The anticoccidial efficacy of amprolium, clazuril, and monensin were studied in sandhill cranes (Grus canadensis) infected with a mixture of Eimeria spp. oocysts. Five groups of four 1-day-old sandhil... |
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Action of the anticoccidial clazuril on the endogenous stages of Eimeria labbeana and E columbarum in experimentally infected pigeons.
Res. Vet. Sci. 45(1) , 117-9, (1988) Racing pigeons were artificially infected with a mixed inoculum of Eimeria labbeana (85 per cent) and E columbarum (15 per cent) and treated orally with 2.5 mg clazuril either on day 1, 2, 3, 4, 5, 6 ... |
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Efficacy of toltrazuril and clazuril against experimental infections with Eimeria labbeana and E. columbarum in racing pigeons.
Avian Dis. 34(1) , 73-9, (1990) The efficacy of toltrazuril in comparison with clazuril on heavy experimental Eimeria labbeana and E. columbarum infections in pigeons was investigated. The minimum required dose of toltrazuril to com... |
| CLAZURIL |
| Clazurilum [Latin] |
| [2-chloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3h)-yl)phenyl](4-chlorophenyl)acetonitrile |
| Clazurilo [Spanish] |
| Clazuril (USAN/INN) |
| Clazurilo |
| Clazurilum |
![2-[3-chloro-4-[chloro(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione结构式](https://www.chemsrc.com/caspic/261/103337-60-6.png)