Clazuril
Clazuril structure
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Common Name | Clazuril | ||
|---|---|---|---|---|
| CAS Number | 101831-36-1 | Molecular Weight | 373.19300 | |
| Density | 1.48g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H10Cl2N4O2 | Melting Point | 196.8° | |
| MSDS | N/A | Flash Point | N/A | |
Use of ClazurilClazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle[1]. |
| Name | 2-[2-chloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]-2-(4-chlorophenyl)acetonitrile |
|---|---|
| Synonym | More Synonyms |
| Description | Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle[1]. |
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| Related Catalog | |
| In Vivo | Clazuril (2.5 mg/pigeon) results in a rapid suppression of oocyst excretion, but oocysts are again observed in the feces 20 days after treatment. The fact that oocysts appears again in the feces 3 to 5 weeks after treatment can probably be explained only by a persistence of endogenous stages, which are not affected during treatment, rather than by a reinfection [2]. |
| References |
| Density | 1.48g/cm3 |
|---|---|
| Melting Point | 196.8° |
| Molecular Formula | C17H10Cl2N4O2 |
| Molecular Weight | 373.19300 |
| Exact Mass | 372.01800 |
| PSA | 91.54000 |
| LogP | 2.88308 |
| Index of Refraction | 1.692 |
| InChIKey | QUUTUGLQZLNABV-UHFFFAOYSA-N |
| SMILES | N#CC(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl |
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~11%
Clazuril CAS#:101831-36-1 |
| Literature: Janssen Pharmaceutica N.V. Patent: US4631278 A1, 1986 ; |
![2-[3-chloro-4-[chloro(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5-(2H,4H)-dione structure](https://image.chemsrc.com/caspic/261/103337-60-6.png)
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Efficacy of selected coccidiostats in sandhill cranes (Grus canadensis) following challenge.
J. Zoo Wildl. Med. 36(3) , 391-400, (2005) The anticoccidial efficacy of amprolium, clazuril, and monensin were studied in sandhill cranes (Grus canadensis) infected with a mixture of Eimeria spp. oocysts. Five groups of four 1-day-old sandhil... |
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Action of the anticoccidial clazuril on the endogenous stages of Eimeria labbeana and E columbarum in experimentally infected pigeons.
Res. Vet. Sci. 45(1) , 117-9, (1988) Racing pigeons were artificially infected with a mixed inoculum of Eimeria labbeana (85 per cent) and E columbarum (15 per cent) and treated orally with 2.5 mg clazuril either on day 1, 2, 3, 4, 5, 6 ... |
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Efficacy of toltrazuril and clazuril against experimental infections with Eimeria labbeana and E. columbarum in racing pigeons.
Avian Dis. 34(1) , 73-9, (1990) The efficacy of toltrazuril in comparison with clazuril on heavy experimental Eimeria labbeana and E. columbarum infections in pigeons was investigated. The minimum required dose of toltrazuril to com... |
| CLAZURIL |
| Clazurilum [Latin] |
| [2-chloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3h)-yl)phenyl](4-chlorophenyl)acetonitrile |
| Clazurilo [Spanish] |
| Clazuril (USAN/INN) |
| Clazurilo |
| Clazurilum |