Clazuril structure
|
Common Name | Clazuril | ||
---|---|---|---|---|
CAS Number | 101831-36-1 | Molecular Weight | 373.19300 | |
Density | 1.48g/cm3 | Boiling Point | N/A | |
Molecular Formula | C17H10Cl2N4O2 | Melting Point | 196.8° | |
MSDS | N/A | Flash Point | N/A |
Use of ClazurilClazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle[1]. |
Name | 2-[2-chloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]-2-(4-chlorophenyl)acetonitrile |
---|---|
Synonym | More Synonyms |
Description | Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle[1]. |
---|---|
Related Catalog | |
In Vivo | Clazuril (2.5 mg/pigeon) results in a rapid suppression of oocyst excretion, but oocysts are again observed in the feces 20 days after treatment. The fact that oocysts appears again in the feces 3 to 5 weeks after treatment can probably be explained only by a persistence of endogenous stages, which are not affected during treatment, rather than by a reinfection [2]. |
References |
Density | 1.48g/cm3 |
---|---|
Melting Point | 196.8° |
Molecular Formula | C17H10Cl2N4O2 |
Molecular Weight | 373.19300 |
Exact Mass | 372.01800 |
PSA | 91.54000 |
LogP | 2.88308 |
Index of Refraction | 1.692 |
~11% Clazuril CAS#:101831-36-1 |
Literature: Janssen Pharmaceutica N.V. Patent: US4631278 A1, 1986 ; |
Efficacy of selected coccidiostats in sandhill cranes (Grus canadensis) following challenge.
J. Zoo Wildl. Med. 36(3) , 391-400, (2005) The anticoccidial efficacy of amprolium, clazuril, and monensin were studied in sandhill cranes (Grus canadensis) infected with a mixture of Eimeria spp. oocysts. Five groups of four 1-day-old sandhil... |
|
Action of the anticoccidial clazuril on the endogenous stages of Eimeria labbeana and E columbarum in experimentally infected pigeons.
Res. Vet. Sci. 45(1) , 117-9, (1988) Racing pigeons were artificially infected with a mixed inoculum of Eimeria labbeana (85 per cent) and E columbarum (15 per cent) and treated orally with 2.5 mg clazuril either on day 1, 2, 3, 4, 5, 6 ... |
|
Efficacy of toltrazuril and clazuril against experimental infections with Eimeria labbeana and E. columbarum in racing pigeons.
Avian Dis. 34(1) , 73-9, (1990) The efficacy of toltrazuril in comparison with clazuril on heavy experimental Eimeria labbeana and E. columbarum infections in pigeons was investigated. The minimum required dose of toltrazuril to com... |
CLAZURIL |
Clazurilum [Latin] |
[2-chloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3h)-yl)phenyl](4-chlorophenyl)acetonitrile |
Clazurilo [Spanish] |
Clazuril (USAN/INN) |
Clazurilo |
Clazurilum |