乐卡地平

• 常用名: 乐卡地平
• 英文名: Lercanidipine
• CAS号: 100427-26-7
• 分子量: 611.727
• 密度: 1.2±0.1 g/cm3
• 沸点: 712.5±60.0 °C at 760 mmHg
• 分子式: C₃₆H₄₁N₃O₆
• 熔点: 118-120ºC
• 闪点: 384.7±32.9 °C

乐卡地平用途

Lercanidipine是钙离子通道阻断剂。

乐卡地平名称

• 中文名: 乐卡地平
• 英文名: 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 中文别名: 1,4-双氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二羧酸 2-[(3,3-二苯丙基)甲氨基]-1,1-二甲基乙基甲酯

乐卡地平生物活性

• 描述: Lercanidipine是钙离子通道阻断剂。
• 相关类别:
  信号通路 >> 跨膜转运 >> 钙通道
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Barrios, V., et al., Lercanidipine is an effective and well tolerated antihypertensive drug regardless the cardiovascular risk profile: The LAURA study. Int J Clin Pract, 2006. 60(11): p. 1364-70.

  [2]. Burnier, M., M. Pruijm, and G. Wuerzner, Treatment of essential hypertension with calcium channel blockers: what is the place of lercanidipine? Expert Opin Drug Metab Toxicol, 2009. 5(8): p. 981-7.

乐卡地平物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 712.5±60.0 °C at 760 mmHg
• 熔点: 118-120ºC
• 分子式: C₃₆H₄₁N₃O₆
• 分子量: 611.727
• 闪点: 384.7±32.9 °C
• 精确质量: 611.299561
• PSA: 113.69000
• LogP: 8.04
• 外观性状: 白色至淡黄色固体
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.580

乐卡地平安全信息

• 海关编码: 2942000000

乐卡地平海关

• 海关编码: 2942000000

乐卡地平英文别名

• 1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester
• lercarnidipine
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester
• methyl 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate
• masnidipine
• Methyl 1,1-Dimethyl-2-[N-(3,3-diphenylpropyl)-N-methylamino]ethyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
• Lercanidipine [INN]
• UNII:V7XTJ4R0BH
• Lercanil (TN)
• (±)-2-((3,3-diphenylpropyl)(methyl)amino)-1,1-dimethylethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• REC 15-2375
• MFCD00867978
• UNII-V7XTJ4R0BH
• 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester
• Lercanidipine