Lercanidipine

Modify Date: 2024-01-03 12:06:17

Lercanidipine Structure
Lercanidipine structure
 Common Name Lercanidipine
CAS Number 100427-26-7 Molecular Weight 611.727
Density 1.2±0.1 g/cm3 Boiling Point 712.5±60.0 °C at 760 mmHg
Molecular Formula C36H41N3O6 Melting Point 118-120ºC
MSDS N/A Flash Point 384.7±32.9 °C

 Use of Lercanidipine


Lercanidipine is a calcium channel blocker of the dihydropyridine class.Target: Calcium ChannelLercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk [1, 2].

 Names

Name 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Synonym More Synonyms

 Lercanidipine Biological Activity

Description Lercanidipine is a calcium channel blocker of the dihydropyridine class.Target: Calcium ChannelLercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk [1, 2].
Related Catalog
References

[1]. Barrios, V., et al., Lercanidipine is an effective and well tolerated antihypertensive drug regardless the cardiovascular risk profile: The LAURA study. Int J Clin Pract, 2006. 60(11): p. 1364-70.

[2]. Burnier, M., M. Pruijm, and G. Wuerzner, Treatment of essential hypertension with calcium channel blockers: what is the place of lercanidipine? Expert Opin Drug Metab Toxicol, 2009. 5(8): p. 981-7.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 712.5±60.0 °C at 760 mmHg
Melting Point 118-120ºC
Molecular Formula C36H41N3O6
Molecular Weight 611.727
Flash Point 384.7±32.9 °C
Exact Mass 611.299561
PSA 113.69000
LogP 8.04
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.580

 Safety Information

HS Code 2942000000

 Customs

HS Code 2942000000

 Synonyms

1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester
lercarnidipine
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester
methyl 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate
masnidipine
Methyl 1,1-Dimethyl-2-[N-(3,3-diphenylpropyl)-N-methylamino]ethyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
Lercanidipine [INN]
UNII:V7XTJ4R0BH
Lercanil (TN)
(±)-2-((3,3-diphenylpropyl)(methyl)amino)-1,1-dimethylethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
REC 15-2375
MFCD00867978
UNII-V7XTJ4R0BH
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester
Lercanidipine
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Related Compounds: More...
lercanidipine oxalate
957215-03-1
(S)-Lercanidipine HCl
184866-29-3
Dehydro Lercanidipine
887769-34-8
lercanidipine L-lactate
877372-41-3
Lercanidipine Impurity 8
210579-71-8
Lercanidipine Impurity 2
75130-24-4
Lercanidipine IMpurity A
74936-74-6
Lercanidipine Impurity 1
89267-42-5
Lercanidipine IMpurity B
1119226-97-9
Chemsrc provides Lercanidipine(CAS#:100427-26-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Lercanidipine are included as well.>> amp version: Lercanidipine

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