159414-98-9

• 常用中文名：N-乙酰基-5'-O-[双(4-甲氧基苯基)苯基甲基]-2'-脱氧-2'-氟胞苷
• 常用英文名：5'-DMT-2'-F-Ac-dC
• CAS号：159414-98-9
• 分子式：C₃₂H₃₂FN₃O₇
• 分子量：589.61100
• 相关类别： 生物化工 核苷类药物 脱氧核苷酸及其类似物
• 发布时间：2018-12-17 12:30:00
• 更新时间：2026-07-14 18:27:25
• 5'-O-DMT-N4-Ac-2'-F-dC是一种经过修饰的核苷,可用于合成DNA或RNA。

名称

• 中文名: N-乙酰基-5’-O-[双(4-甲氧基苯基)苯基甲基]-2’-脱氧-2’-氟胞苷
• 英文名: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
• 中文别名: N4-乙酰基-5'-O-DMT-2'-氟-脱氧胞苷; N-(1-((2R,3R,4R,5R)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-3-氟-4-羟基四氢呋喃-2-基)-2-氧代-1,2-二氢嘧啶-4-基)乙酰胺; N4-乙酰基-5'-O-(4,4'-二甲氧基三苯甲基)-2'-氟-2'-脱氧胞苷; N-乙酰基-5'-O-(4,4'-二甲氧基三苯甲基)]-2'-脱氧-2'-氟胞苷; DMT保护性-N4-乙酰基-2'-氟脱氧胞苷; N4-乙酰基-5'-O-[双(4-甲氧基苯基)苯甲基]-2'-氟-2'-脱氧胞苷; 5'-DMT-2'-氟-乙酰基-2'-脱氧胞苷; 5'-O-DMT-2'-氟-N4-乙酰基脱氧胞苷; N-乙酰基-5`-O-[双(4-甲氧基苯基)苯基甲基]-2`-脱氧-2`-氟胞苷
• 英文别名: 5'-O-DMT-N4-acetyl-2'-fluoro-2'-deoxycytidine; 5'-O-DMTr-2'-F-dC(Ac); 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE; DMT-N4-Ac-2'-F-dC; 5'-O-DMT-N4-ACETYL-2'-FLUORO-2'-DEOXYCYTIDINE; 5'-O-DMT-2'-F-Acetyl-Deoxycytidine; N-(1-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyriMidin-4-yl)acetaMide; N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; DMT-2'-F-dCAc; N4-Ac-DMT-2'-F-dC; 2'-FLUORO-5'-O-DIMETHOXYTRITYL-N4-ACETYL-D-CYTIDINE //BP; 5'-O-DMT-N4-Ac-2'-F-dC; HG1118; 5'-ODMT-2'-Fluoro-N-Ac Cytidine; N4-ACETYL-2'-DEOXY-2'-FLUORO-5'-O-DMT-D-CYTIDINE; DMT-2'-FAc-C; N4-ACETYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-FLUORO-D-CYTIDINE; N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; DMT-2'-F-Ac-dC; N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-fluoro-2’-deoxycytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-cytidine; N4-Acetyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine; DMT-2'-F-C(Ac); 5'-O-(4, 4'-dimethoxytrityl)-N4-acetyl-2'-fluoro-2'-deoxycytidine; 5'-O-DMT- N4-Ac-2'-F-dC. 5'-O-(4, 4'-dimethoxytrityl)-N4-acetyl-2'-fluoro-2'-deoxycytidine; 5'-O-DMT-2'-F-N4-acetyl-deoxycytidine; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro; DMT-2'-F-Ac-C; 5'-O-DMT-2'-F-Ac-dC; N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine; N4-Acetyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-Fluoro-2'-Deoxycytidine

物化性质

• 密度: 1.31±0.1 g/cm3(Predicted)
• 分子式: C₃₂H₃₂FN₃O₇
• 分子量: 589.61100
• 精确质量: 589.22200
• PSA: 121.14000
• LogP: 3.89700
• 储存条件: 2-8℃，干燥

生物活性

• 描述: 5'-O-DMT-N4-Ac-2'-F-dC是一种经过修饰的核苷,可用于合成DNA或RNA。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 感染
  信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成
  信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物