160081-62-9

160081-62-9结构式

常用中文名：2-氯-5-(4-甲氧基螺1,2-二氧杂环丁烷-3,2′-(5-氯三环3.3.1.13.7癸烷)-4-基 -1-苯基磷酸二钠
常用英文名：CDP-Star
CAS号：160081-62-9
分子式：C₁₈H₁₉Cl₂Na₂O₇P
分子量：495.199
相关类别：信号通路代谢酶/蛋白酶磷酸酶
发布时间：2018-11-25 18:19:51
更新时间：2024-01-09 18:56:35
CDP Star是碱性磷酸酶的化学发光底物。CDP-Star可用于酶联免疫测定[1]。

中文名	CDP STAR SUBSTRATE
英文名	CDP-Star Chemiluminescent Substrate
英文别名	Disodium 4-chloro-3-[(1'R,3'S,5's)-5'-chloro-4-methoxyspiro[1,2-dioxetane-3,2'-tricyclo[3.3.1.1]decan]-4-yl]phenyl phosphate Disodium 4-chloro-3-[(1'R,3'S,5's,7's)-5'-chloro-4-methoxyspiro[1,2-dioxetane-3,2'-tricyclo[3.3.1.1]decan]-4-yl]phenyl phosphate Phenol, 4-chloro-3-[(1'R,3'S)-5'-chloro-4-methoxyspiro[1,2-dioxetane-3,2'-tricyclo[3.3.1.1]decan]-4-yl]-, dihydrogen phosphate, sodium salt (1:2) disodium,[4-chloro-3-[(3R,5S)-1-chloro-3'-methoxyspiro[adamantane-4,4'-dioxetane]-3'-yl]phenyl] phosphate Chemiluminescent Substrate

描述	CDP Star是碱性磷酸酶的化学发光底物。CDP-Star可用于酶联免疫测定[1]。
相关类别	信号通路 >> 代谢酶/蛋白酶 >> 磷酸酶研究领域 >> 其他
体外研究	指南(以下是我们推荐的协议。本协议仅提供指南,应根据您的具体需求进行修改)。1.将待检测物质 (磷酸酶模拟物) 与化学发光底物 CDP星形(25μM)混合在20 mM HEPES缓冲液(pH值8.5)中。 2.在室温下立即测量混合物的时间依赖性化学发光强度。
参考文献	[1]. Hu L, et al. Chemiluminescence of the Ce(IV)/CDP-Star System Based on the Phosphatase-like Activity of Ce(IV) Ions. ACS Omega. 2021 Feb 25;6(9):6379-6384.

分子式	C₁₈H₁₉Cl₂Na₂O₇P
分子量	495.199
精确质量	494.004089
PSA	109.92000
LogP	5.00520
外观性状	无色液体
储存条件	2-8°C

Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
Product name: CDP-Star® Chemiluminescent Substrate
Relevant identified uses of the substance or mixture and uses advised against
Identified uses: Laboratory chemicals, Manufacture of substances

Section2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.
Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogramnone
Signal wordnone
Hazard statement(s)none
Precautionary statement(s) none
Supplemental Hazardnone
Statements
Safety data sheet available on request.
Safety data sheet available on request for professional users.
Other hazards - none

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Mixtures
: Disodium 2-chloro-5-(4-methoxyspiro[1,2-dioxetane-3,2′-(5-
Synonyms
chlorotricyclo[3.3.1.13.7]decan])-4-yl]-1-phenyl phosphate
ComponentClassificationConcentration
Buffer Solution
Skin Irrit. 2; Eye Irrit. 2; STOT < 10 %
SE 3; H315, H319, H335
Xi, R36/37/38
2-Chloro-5-(4-methoxyspiro{1,2-dioxetane-3,2'-(5'-chloro)-tricyclo[3.3.1.1]decan}-4-yl)-1-phenyl
phosphate disodium salt (cdp-star)
CAS-No.160081-62-9Skin Irrit. 2; Eye Irrit. 2; H315, < 10 %
H319
Xi, R36/37/38
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

Section4. FIRST AID MEASURES
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
no data available

Section5. FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Oxides of phosphorus, Hydrogen chloride gas, Sodium oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

Section7. HANDLING AND STORAGE
Precautions for safe handling
no data available
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature: 2 - 8 °C
Light sensitive. Heat sensitive.
Specific end uses
no data available

Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) AppearanceForm: liquid
b) Odourno data available
c) Odour Thresholdno data available
d) pHno data available
e) Melting point/freezingno data available
point
f) Initial boiling point and no data available
boiling range
g) Flash pointno data available
h) Evaporation rateno data available
i) Flammability (solid, gas) no data available
j) Upper/lowerno data available
flammability or
explosive limits
k) Vapour pressureno data available
l) Vapour densityno data available
m) Relative densityno data available
n) Water solubilityno data available
o) Partition coefficient: n- no data available
octanol/water
p) Autoignitionno data available
temperature
q) Decompositionno data available
temperature
r) Viscosityno data available
s) Explosive propertiesno data available
t) Oxidizing propertiesno data available
Other safety information
no data available

Section10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products

Section11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC:No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation
May be harmful if inhaled. May cause respiratory tract irritation.
IngestionMay be harmful if swallowed.
SkinMay be harmful if absorbed through skin. May cause skin irritation.
EyesMay cause eye irritation.
Additional Information
RTECS: Not available

Section12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

Section13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

Section14. TRANSPORT INFORMATION
UN number
ADR/RID: -IMDG: -IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA:Not dangerous goods
Transport hazard class(es)
ADR/RID: -IMDG: -IATA: -
Packaging group
ADR/RID: -IMDG: -IATA: -
Environmental hazards
ADR/RID: noIMDG Marine pollutant: noIATA: no
Special precautions for user
no data available

SECTION 15 - REGULATORY INFORMATION
N/A

SECTION 16 - ADDITIONAL INFORMATION
N/A

危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	R36/37/38
安全声明 (欧洲)	26-36
危险品运输编码	NONH for all modes of transport

2308481-14-1	2171444-92-9
2171275-74-2	2227934-32-7
2172098-10-9	2172344-15-7
2172344-17-9	2172043-95-5
2171765-90-3	2172098-18-7