84766-91-6

• 常用中文名：2-羟基-1-吡咯烷羧酸叔丁酯
• 常用英文名：N-boc prrolidin-2-ol
• CAS号：84766-91-6
• 分子式：C₉H₁₇NO₃
• 分子量：187.236
• 发布时间：2018-07-09 10:03:18
• 更新时间：2025-08-23 09:25:24

名称

• 中文名: 2-羟基-1-吡咯烷羧酸叔丁酯
• 英文名: tert-butyl 2-hydroxypyrrolidine-1-carboxylate
• 英文别名: N-tert-butoxycarbonyl-2-hydroxypyrrolidine; TERT-BUTYL 2-HYDROXY-1-PYRROLIDINECARBOXYLATE; 2-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester; 2-Methyl-2-propanyl 2-hydroxy-1-pyrrolidinecarboxylate; 1-Pyrrolidinecarboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester; N-boc prrolidin-2-ol; N-tert-butylcarbonyl-2-(p-methoxyphenylsulfanyl)pyrrolidine; 1-tert-butyloxycarbonyl-2-hydroxypyrrolidine; t-butyl 2-hydroxypyrrolidine-1-carboxylate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 273.3±33.0 °C at 760 mmHg
• 分子式: C₉H₁₇NO₃
• 分子量: 187.236
• 闪点: 119.1±25.4 °C
• 精确质量: 187.120850
• PSA: 49.77000
• LogP: 0.13
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.502
• 储存条件: 2-8℃

安全

• 危害码 (欧洲): Xi

合成路线

85909-08-6 ~99% 84766-91-6

文献：Yoshitomi, Yayoi; Arai, Hiromi; Makino, Kazuishi; Hamada, Yasumasa Tetrahedron, 2008 , vol. 64, # 51 p. 11568 - 11579

75178-87-9 ~72% 84766-91-6

文献：Kokotos, Christoforos G.; Aggarwal, Varinder K. Chemical Communications, 2006 , # 20 p. 2156 - 2158

201230-82-2 78888-18-3 ~% 84766-91-6

文献：Schmidt, Axel M.; Eilbracht, Peter Organic and Biomolecular Chemistry, 2005 , vol. 3, # 12 p. 2333 - 2343

6346-09-4 24424-99-5 ~% 84766-91-6

文献：Merck and Co., Inc. Patent: US4634715 A1, 1987 ; US 4634715 A

15761-39-4 ~65% 84766-91-6

文献：Kaname; Mashige; Yoshifuji Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 5 p. 531 - 536

24424-99-5 ~% 84766-91-6

文献：Gawley, Robert E.; Barolli, Graciela; Madan, Sachin; Saverin, Michele; O'Connor, Sean Tetrahedron Letters, 2004 , vol. 45, # 8 p. 1759 - 1761

201230-82-2 78888-18-3 ~% 84766-91-6 374729-55-2 详细

文献：Zhang, Xiaowei; Cao, Bonan; Yu, Shichao; Zhang, Xumu Angewandte Chemie - International Edition, 2010 , vol. 49, # 24 p. 4047 - 4050

201230-82-2 78888-18-3 ~% 84766-91-6 374729-55-2

文献：Zhang, Xiaowei; Cao, Bonan; Yu, Shichao; Zhang, Xumu Angewandte Chemie - International Edition, 2010 , vol. 49, # 24 p. 4047 - 4050

86953-79-9 ~% 84766-91-6

文献：Mori, Miwako; Washioka, Yumiko; Urayama, Takao; Yoshiura, Kagari; Chiba, Katsumi; Ban, Yoshio Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4058 - 4067