5957-75-5

• 常用中文名：DEA限制
• 常用英文名：(−)-trans-Δ8-tetrahydrocannabinol
• CAS号：5957-75-5
• 分子式：C₂₁H₃₀O₂
• 分子量：314.462
• 相关类别： 分析化学 标准品 标准物质
• 发布时间：2018-09-28 18:47:24
• 更新时间：2024-01-04 00:41:59

名称

• 中文名: (-)-Δ8-四氢大麻酚
• 英文名: 8-Tetrahydro Cannabinol
• 英文别名: 6H-Dibenzo[b,d]pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-; D8-THC; δ6-THC; δ8-Tetrahydrocannabinol; δ-8-THC; (6aR,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-1-ol; δ8-THC; (-)-D6-3,4-trans-Tetrahydro-6,6,9-tri methyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol\; 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-; D6-THC; 6H-Dibenzo[b,d]pyran-1-ol, 6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 383.5±42.0 °C at 760 mmHg
• 分子式: C₂₁H₃₀O₂
• 分子量: 314.462
• 闪点: 144.5±22.1 °C
• 精确质量: 314.224579
• PSA: 29.46000
• LogP: 7.53
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.529

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HP8400000 CHEMICAL NAME : 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,10,10a-tetrahydro-3-pentyl-6,6,9-trimethyl-, trans(-)- CAS REGISTRY NUMBER : 5957-75-5 BEILSTEIN REFERENCE NO. : 0023921 LAST UPDATED : 199612 DATA ITEMS CITED : 19 MOLECULAR FORMULA : C21-H30-O2 MOLECULAR WEIGHT : 314.51 WISWESSER LINE NOTATION : T B666 HO MU&TTJ CQ E5 I1 I1 M1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 860 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 560 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - analgesia TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 97 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - analgesia TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 210 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 27500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >3 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : >3150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 59500 mg/kg/17W-I TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - aggression Related to Chronic Data - death TYPE OF TEST : DNA inhibition MUTATION DATA TEST SYSTEM : Rodent - mouse DOSE/DURATION : 200 mg/kg REFERENCE : RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 17,703,1977

安全

• 符号: GHS02, GHS06, GHS08
• 信号词: Danger
• 危害声明: H225-H301 + H311 + H331-H370
• 警示性声明: P210-P260-P280-P301 + P310-P311
• 危害码 (欧洲): F: Flammable;
• 风险声明 (欧洲): 11-39/23/24/25-23/24/25
• 安全声明 (欧洲): 7-16-36/37-45
• 危险品运输编码: UN 1170