查看所有供应商和价格请点击：
| 中文名 | 盐酸后马托品 |
|---|---|
| 英文名 | (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate,hydrochloride |
| 中文别名 | 后马托品盐酸盐 |
| 英文别名 |
HOMATROPINE HCL
AC1Q3EBX DL-Mandelsaeure-tropan-3endo-ylester,Hydrochlorid Homatropine hydrochloride 8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetatehydrochloride(1:1) CTK8B4043 UNII-365MO3S3N9 DL-mandelic acid-tropane-3endo-ylester,hydrochloride 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,hydrochloride EINECS 211-280-0 MFCD00050613 AC1L2STU |
| 描述 | Homatropine hydrochloride 是一种口服有效的抗胆碱能剂,能迅速放大瞳孔,具有睫状肌麻痹作用。Homatropine hydrochloride 还有镇咳活性。Homatropine hydrochloride 可用于眼部疾病以及止咳的研究。 |
|---|---|
| 相关类别 | |
| 参考文献 |
| 沸点 | 403.3ºC at 760 mmHg |
|---|---|
| 熔点 | 226ºC |
| 分子式 | C16H22ClNO3 |
| 分子量 | 311.80 |
| 闪点 | 197.7ºC |
| 精确质量 | 311.12900 |
| PSA | 49.77000 |
| LogP | 2.62830 |
| 外观性状 | 白色-类白色晶体-粉末 |
| 储存条件 | 存放在密封容器内，并放在阴凉，干燥处。储存的地方必须远离氧化剂，远离火源。 |
| 稳定性 | 远离氧化物。 |
| 分子结构 | 1、 摩尔折射率：76.15 2、 摩尔体积（m3/mol）：226.1 3、 等张比容（90.2K）：606.0 4、 表面张力（dyne/cm）：51.5 5、 极化率（10-24cm3）：30.19 |
| 计算化学 | 1、 疏水参数计算参考值（XlogP）： 2、 氢键供体数量：2 3、 氢键受体数量：4 4、 可旋转化学键数量：4 5、 拓扑分子极性表面积（TPSA）：49.8 6、 重原子数量：21 7、 表面电荷：0 8、 复杂度：340 9、 同位素原子数量：0 10、 确定原子立构中心数量：0 11、 不确定原子立构中心数量：0 12、 确定化学键立构中心数量：0 13、 不确定化学键立构中心数量：0 14、 共价键单元数量：1 |
| 更多 | 1. 性状：结晶性粉末。 2. 密度（g/mL,25/4℃）：未确定 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：121 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC,5.2kPa）：未确定 7. 折射率：未确定 8. 闪点（ºC）：未确定 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（kPa,25ºC）：未确定 12. 饱和蒸气压（kPa,60ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（KPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：未确定 。 |
|
Homatropine Hydrochloride
SAFETY DATA SHEET Section1. IDENTIFICATION Product name:Homatropine Hydrochloride Section2. HAZARDS IDENTIFICATION GHS classification
PHYSICAL HAZARDSNot classified
HEALTH HAZARDS Acute toxicity (Oral)Category 3 Category 3 Acute toxicity (Dermal) Acute toxicity (Inhalation)Category 3 Not classified ENVIRONMENTAL HAZARDS GHS label elements, including precautionary statements Pictograms or hazard symbols Signal wordDanger Hazard statementsToxic if swallowed, in contact with skin or if inhaled Precautionary statements: Avoid breathing dust/fume/gas/mist/vapours/spray. [Prevention] Use only outdoors or in a well-ventilated area. Do not eat, drink or smoke when using this product. Wash hands thoroughly after handling. Wear protective gloves and eye/face protection. [Response]IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. IF ON SKIN: Gently wash with plenty of soap and water. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. [Storage]Store in a well-ventilated place. Keep container tightly closed. Store locked up. [Disposal]Dispose of contents/container through a waste management company authorized by the local government. Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance Substance/mixture: Homatropine Hydrochloride Section3. COMPOSITION/INFORMATION ON INGREDIENTS Components:Homatropine Hydrochloride Percent:>98.0%(T) CAS Number:637-21-8 Chemical Formula:C16H21NO3·HCl Section4. FIRST AID MEASURES Remove victim to fresh air and keep at rest in a position comfortable for breathing. Inhalation: Call a POISON CENTER or doctor/physician. Remove/Take off immediately all contaminated clothing. Gently wash with plenty of Skin contact: soap and water. Call a POISON CENTER or doctor/physician. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air- tight goggles. Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, water spray, carbon dioxide. media: Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to from the chemical:generate poisonous fume. Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Use extra personal protective equipment (P3 filter respirator for toxic particles). Keep Personal precautions, protective equipment and people away from and upwind of spill/leak. Entry to non-involved personnel should emergency procedures: be controlled around the leakage area by roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it. containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with up: appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent dispersion of dust. Wash hands and face thoroughly after handling. Use a closed system if possible. Use a local exhaust if dust or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a cool, dark and well-ventilated place. Store locked up. Store away from incompatible materials such as oxidizing agents. Packaging material:Comply with laws. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Install a closed system or local exhaust. Also install safety shower and eye bath. Engineering controls: Personal protective equipment Homatropine Hydrochloride Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Respiratory protection: Dust respirator, self-contained breathing apparatus(SCBA), supplied air respirator, etc. Use respirators approved under appropriate government standards and follow local and national regulations. Hand protection:Impervious gloves. Eye protection:Safety goggles. A face-shield, if the situation requires. Skin and body protection: Impervious protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Solid Physical state (20°C): Form:Crystal- Powder Colour:White - Almost white Odour:No data available pH: No data available Melting point/freezing point:220°C Boiling point/range:No data available Flash point:No data available Flammability or explosive limits: Lower:No data available Upper:No data available Relative density:No data available Solubility(ies): [Water]No data available [Other solvents]No data available Section10. STABILITY AND REACTIVITY Chemical stability:Stable under proper conditions. Possibility of hazardous No special reactivity has been reported. reactions: Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride products: Section11. TOXICOLOGICAL INFORMATION Acute Toxicity:No data available Skin corrosion/irritation: No data available Serious eyeNo data available damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available Reproductive toxicity:No data available Section12. ECOLOGICAL INFORMATION Ecotoxicity: No data available Fish: Crustacea:No data available No data available Algae: Persistence / degradability: No data available No data available Bioaccumulative potential(BCF): Mobility in soil Log Pow:No data available No data available Soil adsorption (Koc): Homatropine Hydrochloride Section12. ECOLOGICAL INFORMATION Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:6.1: Toxic substance. 1544 UN-No: Proper shipping name:Alkaloid salts, solid, n.o.s. Packing group:III Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. SECTION 16 - ADDITIONAL INFORMATION N/A |
|
生态学数据: 通常对水是不危害的，若无政府许可，勿将材料排入周围环境。
|
| 危害码 (欧洲) | Xn |
|---|---|
| 危险品运输编码 | UN 1544 6.1/PG 3 |
| 包装等级 | III |
| 海关编码 | 2933990090 |
| 海关编码 | 2933990090 |
|---|---|
| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |