2095625-97-9

• 常用中文名：Milademetan tosylate hydrate
• 常用英文名：Milademetan tosylate hydrate
• CAS号：2095625-97-9
• 分子式：C₃₇H₄₄Cl₂FN₅O₈S
• 分子量：808.743
• 发布时间：2021-01-08 14:53:09
• 更新时间：2025-09-01 19:36:48
• Milademetan (DS-3032) tosylate hydrate is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis.

名称

• 英文名: (3'R,4'S,5'R)-N-[(3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl]-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1) (non-preferred name)

物化性质

• 分子式: C₃₇H₄₄Cl₂FN₅O₈S
• 分子量: 808.743
• 精确质量: 807.227173