2095625-97-9

2095625-97-9 structure

Name: Milademetan tosylate hydrate
Chemical Name: (3'R,4'S,5'R)-N-[(3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl]-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1) (non-preferred name)
CAS Number: 2095625-97-9
Molecular Formula: C₃₇H₄₄Cl₂FN₅O₈S
Molecular Weight: 808.743
Create Date: 2021-01-08 14:53:09
Modify Date: 2025-09-01 19:36:48
Milademetan (DS-3032) tosylate hydrate is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis.

Name	(3'R,4'S,5'R)-N-[(3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl]-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1) (non-preferred name)