Milademetan tosylate hydrate

Modify Date: 2025-09-01 19:36:48

Milademetan tosylate hydrate Structure
Milademetan tosylate hydrate structure
Common Name Milademetan tosylate hydrate
CAS Number 2095625-97-9 Molecular Weight 808.743
Density N/A Boiling Point N/A
Molecular Formula C37H44Cl2FN5O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Milademetan tosylate hydrate


Milademetan (DS-3032) tosylate hydrate is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis.

 Names

Name (3'R,4'S,5'R)-N-[(3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl]-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide 4-methylbenzenesulfonate hydrate (1:1:1) (non-preferred name)

 Chemical & Physical Properties

Molecular Formula C37H44Cl2FN5O8S
Molecular Weight 808.743
Exact Mass 807.227173
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