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溶葡球菌酶

溶葡球菌酶用途

Lysostaphin一种抗葡萄球菌剂。Lysostaphin 对甘氨酸内肽酶、内源性β-N乙酰化葡糖苷酶,以及N乙酰化胞壁酰丙氨酸酰胺酶有抑制活性。

溶葡球菌酶名称

[ CAS 号 ]:
9011-93-2

[ 中文名 ]:
溶葡球菌酶

[ 英文名 ]:
Lysostaphin

[英文别名 ]:

2-(3,5-Dimethoxyphenyl)-4(1H)-quinazolinone
2-(3,5-dimethoxyphenyl)quinazolin-4-ol
4(1H)-Quinazolinone, 2-(3,5-dimethoxyphenyl)-

溶葡球菌酶生物活性

[ 描述 ]:

Lysostaphin一种抗葡萄球菌剂。Lysostaphin 对甘氨酸内肽酶、内源性β-N乙酰化葡糖苷酶,以及N乙酰化胞壁酰丙氨酸酰胺酶有抑制活性。

[ 相关类别 ]:

研究领域 >> 感染

研究领域 >> 炎症/免疫

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Jaspal K Kumar, et al. Lysostaphin: An Antistaphylococcal Agent. Appl Microbiol Biotechnol. 2008 Sep;80(4):555-61.

溶葡球菌酶物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
483.6±55.0 °C at 760 mmHg

[ 分子式 ]:
C₁₆H₁₄N₂O₃

[ 分子量 ]:
282.294

[ 闪点 ]:
246.3±31.5 °C

[ 精确质量 ]:
282.100433

[ LogP ]:
2.18

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.618

[ 储存条件 ]:
-20°C

溶葡球菌酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S22;S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
OL5985000

溶葡球菌酶文献

Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.

Infect. Immun. 76(4) , 1333-9, (2008)

Thymidine-dependent small-colony variants (SCVs) of Staphylococcus aureus are frequently associated with persistent and recurrent infections in cystic fibrosis patients. The phenotypic appearance of S...

Targeting methicillin-resistant Staphylococcus aureus with short salt-resistant synthetic peptides.

Antimicrob. Agents Chemother. 58(7) , 4113-22, (2014)

The seriousness of microbial resistance combined with the lack of new antimicrobials has increased interest in the development of antimicrobial peptides (AMPs) as novel therapeutics. In this study, we...

Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein.

FEBS Lett. 587(5) , 404-9, (2013)

Leukocyte cell-derived chemotaxin 2 (LECT2) is a secreted hepatic protein that has been associated with several physiological activities. LECT2 belongs to the peptidase M23 family, suggesting that it ...

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