溶菌酶

溶菌酶用途

人乳溶菌酶是在人乳中发现的溶菌酶。母乳溶菌酶被认为是保护新生儿胃肠道免受细菌感染的关键防御因素[1]。

溶菌酶名称

[ CAS 号 ]:
12671-19-1

[ 中文名 ]:
溶菌酶

[ 英文名 ]:
Human milk lysozyme

[英文别名 ]:

EINECS 235-747-3

溶菌酶生物活性

[ 描述 ]:

人乳溶菌酶是在人乳中发现的溶菌酶。母乳溶菌酶被认为是保护新生儿胃肠道免受细菌感染的关键防御因素[1]。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[体外研究]

母乳溶菌酶(0-300μg/mL；2小时)对皮肤病原体痤疮预防和微小C.tissimum表现出优异的活性。母乳溶菌酶对革兰氏阴性大肠杆菌、沙门氏菌。鼠伤寒和博尔德。支气管败血症缺乏活性,但对克莱布。肺炎和铜绿假单胞菌有较弱的活性。母乳溶菌酶对体育场。表皮病无活性,对体育场。金黄色葡萄球菌和动物流行病史的活性较弱[1]。

[参考文献]

[1]. Ibrahim HR, et al. Human lysozyme possesses novel antimicrobial peptides within its N-terminal domain that target bacterial respiration. J Agric Food Chem. 2011 Sep 28;59(18):10336-45.

溶菌酶物理化学性质

[ 外观性状 ]:
powder

[ 储存条件 ]:
2-8°C

溶菌酶安全信息

[ 危害码 (欧洲) ]:
B

[ 安全声明 (欧洲) ]:
23-24/25-22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
OL5989850

溶菌酶文献

Sequential separation of lysozyme, ovomucin, ovotransferrin, and ovalbumin from egg white.

Poult. Sci. 93(4) , 1001-9, (2014)

Ovalbumin, ovotransferrin, ovomucin, and lysozyme are a few of the egg white proteins that can be used as functional components. The objective of this study was to develop a simple, sequential separat...

The periplasmic disulfide oxidoreductase DsbA contributes to Haemophilus influenzae pathogenesis.

Infect. Immun. 76(4) , 1498-508, (2008)

Haemophilus influenzae is an obligate human pathogen that persistently colonizes the nasopharynx and causes disease when it invades the bloodstream, lungs, or middle ear. Proteins that mediate critica...

Refolding of SDS-denatured proteins using amphipathic cosolvents and osmolytes.

Curr. Protoc. Protein Sci. Chapter 28 , Unit28.5, (2013)

Currently, the investigation of protein refolding processes involves several time-consuming stages that require large amounts of protein and costly chemicals. Consequently, there is great interest in ...

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溶菌酶