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5-氨基-1-萘磺酸

5-氨基-1-萘磺酸用途

【用途一】
用于制备酸性染料和活性染料，也是制1-萘酚-5-磺酸的中间体
【用途二】
该品是偶氮染料的中间体，也用于制造1-萘酚磺酸类产品。
【用途三】
该品是偶氮染料(酸性染料和活性染料)的中间体，也用于制造1-萘酚磺酸类产品。

5-氨基-1-萘磺酸名称

[ CAS 号 ]:
84-89-9

[ 中文名 ]:
1-萘胺-5-磺酸

[ 英文名 ]:
1-naphthylamine-5-sulfonic acid

[中文别名 ]:

[英文别名 ]:

1-naphthylamine-5-sulfonic acid
5-Amino-1-naphthalenesulfonic acid
5-Aminonaphthalene-1-sulfonic acid
MFCD00014315
1-Naphthalenesulfonic acid, 5-amino-
EINECS 201-571-0

5-氨基-1-萘磺酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 熔点 ]:
>300°C

[ 分子式 ]:
C₁₀H₉NO₃S

[ 分子量 ]:
223.248

[ 精确质量 ]:
223.030319

[ PSA ]:
88.77000

[ LogP ]:
0.42

[ 外观性状 ]:
白色或淡粉红色针状晶体

[ 折射率 ]:
1.713

[ 储存条件 ]:
库房通风低温干燥

5-氨基-1-萘磺酸MSDS

5-氨基-1-萘磺酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QK1270500

CHEMICAL NAME :: 1-Naphthalenesulfonic acid, 5-amino-

CAS REGISTRY NUMBER :: 84-89-9

BEILSTEIN REFERENCE NO. :: 2214149

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H9-N-O3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - muscle weakness

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2880 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Behavioral - muscle weakness

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2990 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 gm/kg/30D-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Liver - liver function tests impaired Blood - pigmented or nucleated red blood cells

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),87,1986

5-氨基-1-萘磺酸安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H312-H314-H332

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R20/21/22;R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2585 8/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
QK1270500

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2921450090

5-氨基-1-萘磺酸合成路线

5-氨基-1-萘磺酸上下游产品

5-氨基-1-萘磺酸上游产品

5-氨基-1-萘磺酸下游产品

5-氨基-1-萘磺酸制备

萘经低温磺化得萘磺酸，同硝酸硝化得5-硝基-1-萘磺酸，再用碳酸镁中和分离出1-萘胺-8-磺酸镁盐，经铁粉还原，硫酸酸化制得周位酸将中和分离得到滤液进行还原，酸化即得1-萘胺-5-磺酸。

5-氨基-1-萘磺酸海关

[ 海关编码 ]: 2921450090

[ 中文概述 ]:
2921450090. 1-萘胺和2-萘胺的衍生物及盐(包括1-萘胺）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

5-氨基-1-萘磺酸文献

Identification of a novel ligand binding motif in the transthyretin channel.

Bioorg. Med. Chem. 18 , 100-10, (2010)

The design of therapeutic compounds targeting transthyretin (TTR) is challenging due to the low specificity of interaction in the hormone binding site. Such feature is highlighted by the interactions ...

[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].

Rinsho Byori. 29(6) , 613-6, (1981)

Evidence for a ppGpp-binding site on Escherichia coli RNA polymerase: proximity relationship with the rifampicin-binding domain.

Mol. Microbiol. 15(2) , 255-65, (1995)

On amino acid starvation, Escherichia coli cells exhibit an adaptive facility termed the stringent response. This is characterized by the production of high levels of a regulatory nucleotide, ppGpp, a...

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