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五甘氨酸

五甘氨酸用途

五甘氨酸(四甘氨酸)是含有五个甘氨酸分子的桥。五甘氨酸可以形成高度交联的肽聚糖。葡萄糖降低了五甘氨酸的表达。五甘氨酸被溶葡萄球菌蛋白酶切割,并出现在葡萄球菌的细胞膜中[1]。

五甘氨酸名称

[ CAS 号 ]:
7093-67-6

[ 中文名 ]:
五甘氨酸

[ 英文名 ]:
Gly-Gly-Gly-Gly-Gly-OH

[英文别名 ]:

N-(N-(N-(N-Glycylglycyl)glycyl)glycyl)glycine
Gly_Gly_Gly_Gly_Gly
MFCD00083696
EINECS 230-398-3
Gly-Gly-Gly-Gly
Gly-Gly-Gly-Gly-Gly-OH
glycylglycylglycylglycylglycine
H-(Gly)5-OH
H-GLY-GLY-GLY-GLY-GLY-OH

五甘氨酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Luo Z, et al. Reduced Growth of Staphylococcus aureus Under High Glucose Conditions Is Associated With Decreased Pentaglycine Expression. Front Microbiol. 2020 Nov 2;11:537290.

五甘氨酸物理化学性质

[ 密度 ]:
1.406g/cm3

[ 沸点 ]:
942.3ºC at 760 mmHg

[ 分子式 ]:
C₁₀H₁₇N₅O₆

[ 分子量 ]:
303.27200

[ 闪点 ]:
523.7ºC

[ 精确质量 ]:
303.11800

[ PSA ]:
179.72000

[ 折射率 ]:
1.543

[ 储存条件 ]:
室温，惰性气体保存

五甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

五甘氨酸合成路线

详细合成路线

五甘氨酸上下游产品

五甘氨酸上游产品

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五甘氨酸文献

Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability.

PLoS ONE 6 , e17054, (2011)

The WalKR two-component system is essential for viability of Staphylococcus aureus, a major pathogen. We have shown that WalKR acts as the master controller of peptidoglycan metabolism, yet none of th...

Modeling the electrophoresis of oligoglycines.

J. Sep. Sci. 33 , 2430-2438, (2010)

The electrophoretic mobility of low molecular mass oligoglycines is examined in this study using a "coarse-grained" bead modeling methodology [Pei, H., Allison, S. A., J. Chromatogr. A 2009, 1216, 190...

Site-specific tetrameric streptavidin-protein conjugation using sortase A.

J. Biotechnol. 152 , 37-42, (2011)

Streptavidin is tetrameric protein which has tight and specific biotin binding affinity, and streptavidin modification of proteins or small molecules is widely used for biotechnology tool. Here, we de...

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