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2-氯乙基乙基硫醚

2-氯乙基乙基硫醚用途

医药中间体

2-氯乙基乙基硫醚名称

[ CAS 号 ]:
693-07-2

[ 中文名 ]:
2-氯乙基乙基硫醚

[ 英文名 ]:
2-Chloroethyl ethyl sulfide

[中文别名 ]:

[英文别名 ]:

MFCD00000979
EINECS 211-742-1
1-chloro-2-ethylsulfanylethane

2-氯乙基乙基硫醚物理化学性质

[ 密度 ]:
1.07

[ 沸点 ]:
156-157 °C

[ 分子式 ]:
C₄H₉ClS

[ 分子量 ]:
124.63200

[ 闪点 ]:
52 °C

[ 精确质量 ]:
124.01100

[ PSA ]:
25.30000

[ LogP ]:
1.97830

[ 外观性状 ]:
透明无色至淡黄色液体

[ 折射率 ]:
1.4875-1.4895

[ 储存条件 ]:
库房低温通风干燥,与食品原料分开存放

[ 水溶解性 ]:
不溶

2-氯乙基乙基硫醚MSDS

2-氯乙基乙基硫醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WQ3250000

CHEMICAL NAME :: Sulfide, chloroethyl ethyl

CAS REGISTRY NUMBER :: 693-07-2

BEILSTEIN REFERENCE NO. :: 0635672

LAST UPDATED :: 199706

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C4-H9-Cl-S

MOLECULAR WEIGHT :: 124.64

WISWESSER LINE NOTATION :: G2S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 252 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 mg/kg/4D-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases

MUTATION DATA

TEST SYSTEM :: Insect - Drosophila melanogaster

DOSE/DURATION :: 5 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 13,19,1971

2-氯乙基乙基硫醚安全信息

[ 符号 ]:

GHS02, GHS05, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H301 + H311 + H331-H314-H350

[ 警示性声明 ]:
P201-P261-P280-P301 + P310-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R10;R22;R36/37/38;R40

[ 安全声明 (欧洲) ]:
S36/37/39-S26-S16-S45-S27

[ 危险品运输编码 ]:
1992

[ RTECS号 ]:
WQ3250000

[ 包装等级 ]:
III

[ 危险类别 ]:
3.2

[ 海关编码 ]:
2930909090

2-氯乙基乙基硫醚合成路线

2-氯乙基乙基硫醚上下游产品

2-氯乙基乙基硫醚上游产品

2-氯乙基乙基硫醚下游产品

2-氯乙基乙基硫醚海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2-氯乙基乙基硫醚文献

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Sulfur mustard (HD) adduct to human serum albumin (ALB) at Cys-34 residue has become an important and long-term retrospective biomarker of HD exposure. Here, a novel, sensitive, and convenient approac...

Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.

Pediatr. Pulmonol. 50(2) , 118-26, (2015)

Inhalation of sulfur mustard (SM) and SM analog, 2-chloroethyl ethyl sulfide (CEES), cause fibrinous cast formation that occludes the conducting airways, similar to children with Fontan physiology-ind...

Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.

Toxicol. Appl. Pharmacol. 272(1) , 86-95, (2013)

Sulfur mustard (SM) inhalation causes airway injury, with enhanced vascular permeability, coagulation, and airway obstruction. The objective of this study was to determine whether recombinant tissue f...

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